Recent advances in gut microbiota-associated natural products: structures, bioactivities, and mechanisms

H Dai, J Han, T Wang, WB Yin, Y Chen, H Liu - Natural product reports, 2023 - pubs.rsc.org
Covering: 2014 to June 2022 The gut microbiota has attracted increasing attention from
researchers due to its critical role in regulating human physiology and pathophysiology …

Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids

XR Peng, SB Unsicker, J Gershenzon… - Natural Product …, 2023 - pubs.rsc.org
Covering: 2018 to 2022 Meroterpenoids found in fungal species of the genus Ganoderma
and known as Ganoderma meroterpenoids (GMs) are substances composed of a 1, 2, 4 …

Gut Parabacteroides merdae protects against cardiovascular damage by enhancing branched-chain amino acid catabolism

S Qiao, C Liu, L Sun, T Wang, H Dai, K Wang… - Nature …, 2022 - nature.com
Obesity, dyslipidemia and gut dysbiosis are all linked to cardiovascular diseases. A
Ganoderma meroterpene derivative (GMD) has been shown to alleviate obesity and …

Flavonoids from Whole-Grain Oat Alleviated High-Fat Diet-Induced Hyperlipidemia via Regulating Bile Acid Metabolism and Gut Microbiota in Mice

R Duan, X Guan, K Huang, Y Zhang, S Li… - Journal of Agricultural …, 2021 - ACS Publications
A high-fat diet (HFD) causes hyperlipidemia, which worsens disturbances in bile acid (BA)
metabolism and gut microbiota. This study aimed to investigate the regulation of flavonoids …

Polysaccharides from Lyophyllum decastes reduce obesity by altering gut microbiota and increasing energy expenditure

T Wang, J Han, H Dai, J Sun, J Ren, W Wang… - Carbohydrate …, 2022 - Elsevier
Polysaccharides are known to confer protection against obesity via modulation of gut
microbiota. To expand our knowledge of mushroom-derived prebiotics, we investigated the …

Gut commensal Christensenella minuta modulates host metabolism via acylated secondary bile acids

C Liu, MX Du, LS Xie, WZ Wang, BS Chen… - Nature …, 2024 - nature.com
A strong correlation between gut microbes and host health has been observed in numerous
gut metagenomic cohort studies. However, the underlying mechanisms governing host …

Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank

C Liu, MX Du, R Abuduaini, HY Yu, DH Li, YJ Wang… - Microbiome, 2021 - Springer
Background In gut microbiome studies, the cultured gut microbial resource plays essential
roles, such as helping to unravel gut microbial functions and host-microbe interactions …

Specific Strains of Faecalibacterium prausnitzii Ameliorate Nonalcoholic Fatty Liver Disease in Mice in Association with Gut Microbiota Regulation

W Hu, W Gao, Z Liu, Z Fang, H Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
Evidence linking Faecalibacterium prausnitzii abundance to nonalcoholic fatty liver disease
(NAFLD) is accumulating; however, the causal relationship remains obscure. In this study …

[HTML][HTML] Dendrobium officinale leaf polysaccharides regulation of immune response and gut microbiota composition in cyclophosphamide-treated mice

H Xie, J Fang, MA Farag, Z Li, P Sun, P Shao - Food Chemistry: X, 2022 - Elsevier
In this study, the polysaccharides extracted from Dendrobium officinale leaf (DOLP) was
used in immune deficiency mice to evaluate the bioactivity. Thymus and spleen indices were …

Lactobacillus rhamnosus LRa05 Ameliorate Hyperglycemia through a Regulating Glucagon-Mediated Signaling Pathway and Gut Microbiota in Type 2 Diabetic Mice

T Wu, Y Zhang, W Li, Y Zhao, H Long… - Journal of Agricultural …, 2021 - ACS Publications
In this study, we aimed to explore the antidiabetic effects of Lactobacillus rhamnosus LRa05
on glucose metabolism and gut microbiota in type 2 diabetes mellitus (T2DM) mice. Our data …