Metal-catalyzed reductive coupling has emerged as an alternative to the use of
stoichiometric organometallic reagents in an increasingly diverse range of carbonyl and …

The activation of a substrate by a chiral catalyst is now regarded as one of the most powerful
strategies that can be employed in the art of asymmetric synthesis. 1 The development of …

Since its advent two decades ago, asymmetric organo/transition-metal combined catalysis
(AOMC), including cooperative catalysis and relay catalysis, has leveraged redistribution of …

Whereas numerous asymmetric methods for formation of quaternary carbon stereocenters in
cyclic systems have been documented, the construction of acyclic quaternary carbon …

Metal-catalyzed regiodivergent reactions allow control over regioselectivity in the synthesis
of a wide range of organic products. Starting from the same material, it is possible to prepare …

Charged intermediates and reagents are ubiquitous in organic transformations. The
interaction of these ionic species with chiral neutral, anionic, or cationic small molecules has …

Supramolecular catalysis is a rapidly expanding discipline which has benefited from the
development of both homogeneous catalysis and supramolecular chemistry. The properties …

Recently, the use of enantiomerically pure counteranions for the induction of asymmetry in
reactions proceeding through cationic intermediates has emerged as an exciting new …

Multicomponent reactions (MCRs) are one-pot processes in which three or more starting
materials form a product that incorporates the structural features of each reagent. These …

Despite the tremendous advances of the past four decades, chemists are far from being able
to use chiral catalysts to control the stereoselectivity of any desired reaction. New concepts …