Sex differences have been well identified in many brain tumors. Even though glioblastoma
(GBM) is the most common primary malignant brain tumor in adults and has the worst …

Inactivation of cancer stem cells (CSCs) is of utmost importance for tumor cure after
radiotherapy. An increasing body of evidence complies with a higher radioresistance of …

Despite all of the progress in understanding its molecular biology and pathogenesis,
glioblastoma (GBM) is one of the most aggressive types of cancers, and without an efficient …

Therapeutic efficacy of glioblastoma multiforme (GBM) is often severely limited by poor
penetration of therapeutics through blood-brain barrier (BBB) into brain tissues and lack of …

The remarkable heterogeneity of glioblastoma, across patients and over time, is one of the
main challenges in precision diagnostics and treatment planning. Non-invasive in vivo …

Glioblastoma is the most common and most aggressive primary brain malignancy. The
current initial standard of care consists of maximal safe surgical resection followed by radical …

BACKGROUND AND PURPOSE: Both IDH1 mutation and MGMT promoter methylation are
associated with longer survival. We investigated the ability of imaging correlates to serve as …

Glioma remains incurable despite great advancements in medicine. Targeting the cell of
origin for gliomas could bring great hope for patients. However, as a collection of diverse …

BACKGROUND AND PURPOSE: WHO grade II gliomas are divided into three classes:
isocitrate dehydrogenase (IDH)-wildtype, IDH-mutant and no 1p/19q codeletion, and IDH …

External beam radiotherapy (RT) has long played a crucial role in the treatment of
glioblastoma. Over the past several decades, significant advances in RT treatment and …