siRNA-based strategies to combat drug resistance in gastric cancer
AQ Khaleel, MY Alshahrani, JA Rizaev, H Malathi… - Medical Oncology, 2024 - Springer
Chemotherapy is a key treatment option for gastric cancer, but over 50% of patients develop
either inherent or acquired resistance to these drugs, resulting in a 5-year survival rate of …
either inherent or acquired resistance to these drugs, resulting in a 5-year survival rate of …
Nanomedicine: a diagnostic and therapeutic approach to COVID-19
The SARS-CoV-2 virus is causing devastating morbidity and mortality worldwide.
Nanomedicine approaches have a high potential to enhance conventional diagnostics …
Nanomedicine approaches have a high potential to enhance conventional diagnostics …
RRM2 regulates sensitivity to sunitinib and PD‐1 blockade in renal cancer by stabilizing ANXA1 and activating the AKT pathway
Renal cell carcinoma (RCC) is a malignant tumor of the kidneys. Approximately 70% of RCC
cases are clear cell renal cell carcinoma with von Hippel–Lindau (VHL) gene mutation and …
cases are clear cell renal cell carcinoma with von Hippel–Lindau (VHL) gene mutation and …
The MAVS immune recognition pathway in viral infection and sepsis
Significance: It is estimated that close to 50 million cases of sepsis result in over 11 million
annual fatalities worldwide. The pathognomonic feature of sepsis is a dysregulated …
annual fatalities worldwide. The pathognomonic feature of sepsis is a dysregulated …
Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer
A Podolski-Renić, AČ Gašparović, A Valente… - European Journal of …, 2024 - Elsevier
Overcoming multidrug resistance (MDR) is one of the major challenges in cancer therapy. In
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …
Identification of ferroptosis related markers by integrated bioinformatics analysis and In vitro model experiments in rheumatoid arthritis
J Xia, L Zhang, T Gu, Q Liu, Q Wang - BMC Medical Genomics, 2023 - Springer
Background Rheumatoid arthritis (RA) is an autoimmune disease characterized by
destructive and symmetrical joint diseases and synovitis. This research attempted to explore …
destructive and symmetrical joint diseases and synovitis. This research attempted to explore …
Systematic analysis of brain and skull ischemic injury expression profiles reveals associations of the tumor immune microenvironment and cell death with ischemic …
C Zhang, L Wang, Y Guo, W Feng - Frontiers in Immunology, 2022 - frontiersin.org
Background Previous studies have shown that stroke is a potential first sign of neoplasia, but
the relationship between stroke and cancer remains unclear. As a complex brain disease …
the relationship between stroke and cancer remains unclear. As a complex brain disease …
[HTML][HTML] Higher concentration of P7C3 than required for neuroprotection suppresses renal cell carcinoma growth and metastasis
G Shu, W Chen, C Huang, H Shan, J Ye, J Li… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background: P7C3 is a novel compound that has been widely applied in neurodegenerative
diseases and nerve injury repair. Here, we show that higher concentrations of P7C3 than …
diseases and nerve injury repair. Here, we show that higher concentrations of P7C3 than …
Applications of nanotechnology in the fight against coronavirus disease 2019
R Sayad, HA Abdelsabour, SM Farhat… - … and Research in …, 2023 - journals.lww.com
Methods: Searching of PubMed, SCOPUS and Google scholar by using a specific search
strategy “(COVID 19 OR COVID-19 Virus Disease OR COVID 19 Virus Infection OR 2019 …
strategy “(COVID 19 OR COVID-19 Virus Disease OR COVID 19 Virus Infection OR 2019 …
IL-27 Enhances γδ T Cell–Mediated Innate Resistance to Primary Hookworm Infection in the Lungs
A Sharma, JB Noon, K Kontodimas… - The Journal of …, 2022 - journals.aai.org
IL-27 is a heterodimeric IL-12 family cytokine formed by noncovalent association of the
promiscuous EBI3 subunit and selective p28 subunit. IL-27 is produced by mononuclear …
promiscuous EBI3 subunit and selective p28 subunit. IL-27 is produced by mononuclear …