A comprehensive review of microneedles: Types, materials, processes, characterizations and applications

FK Aldawood, A Andar, S Desai - Polymers, 2021 - mdpi.com
Drug delivery through the skin offers many advantages such as avoidance of hepatic first-
pass metabolism, maintenance of steady plasma concentration, safety, and compliance over …

Enhancing permeation of drug molecules across the skin via delivery in nanocarriers: novel strategies for effective transdermal applications

YQ Yu, X Yang, XF Wu, YB Fan - Frontiers in bioengineering and …, 2021 - frontiersin.org
The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Non-invasive delivery strategies for biologics

AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …

Nanocrystals as a master key to deliver hydrophobic drugs via multiple administration routes

MB McGuckin, J Wang, R Ghanma, N Qin… - Journal of Controlled …, 2022 - Elsevier
The poor aqueous solubility of many approved drugs and most new chemical entities poses
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …

Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment

ZJ Krysiak, U Stachewicz - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
The skin is a complex layer system and the most important barrier between the environment
and the organism. In this review, we describe some widespread skin problems, with a focus …

Transdermal drug delivery: innovative pharmaceutical developments based on disruption of the barrier properties of the stratum corneum

A Zaid Alkilani, MTC McCrudden, RF Donnelly - Pharmaceutics, 2015 - mdpi.com
The skin offers an accessible and convenient site for the administration of medications. To
this end, the field of transdermal drug delivery, aimed at developing safe and efficacious …

The potential of plant phenolics in prevention and therapy of skin disorders

M Działo, J Mierziak, U Korzun, M Preisner… - International journal of …, 2016 - mdpi.com
Phenolic compounds constitute a group of secondary metabolites which have important
functions in plants. Besides the beneficial effects on the plant host, phenolic metabolites …

Advances in transdermal insulin delivery

Y Zhang, J Yu, AR Kahkoska, J Wang, JB Buse… - Advanced drug delivery …, 2019 - Elsevier
Insulin therapy is necessary to regulate blood glucose levels for people with type 1 diabetes
and commonly used in advanced type 2 diabetes. Although subcutaneous insulin …

Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects

S Barua, S Mitragotri - Nano today, 2014 - Elsevier
Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Transdermal patches: history, development and pharmacology

MN Pastore, YN Kalia, M Horstmann… - British journal of …, 2015 - Wiley Online Library
Transdermal patches are now widely used as cosmetic, topical and transdermal delivery
systems. These patches represent a key outcome from the growth in skin science …