Guidelines for assessment of bone microstructure in rodents using micro–computed tomography

ML Bouxsein, SK Boyd, BA Christiansen… - Journal of bone and …, 2010 - academic.oup.com
Use of high‐resolution micro–computed tomography (µCT) imaging to assess trabecular
and cortical bone morphology has grown immensely. There are several commercially …

Mechanical signaling for bone modeling and remodeling

AG Robling, CH Turner - Critical Reviews™ in Eukaryotic Gene …, 2009 - dl.begellhouse.com
Proper development of the skeleton in utero and during growth requires mechanical
stimulation. Loading results in adaptive changes in bone that strengthen bone structure …

[图书][B] Microcomputed tomography: methodology and applications

SR Stock - 2019 - taylorfrancis.com
MicroComputed Tomography has become the gold standard for studying 3D microscopic
structures nondestructively, and this book provides up-to-date coverage of the modality. The …

Peripheral cannabinoid receptor, CB2, regulates bone mass

O Ofek, M Karsak, N Leclerc, M Fogel… - Proceedings of the …, 2006 - National Acad Sciences
The endogenous cannabinoids bind to and activate two G protein-coupled receptors, the
predominantly central cannabinoid receptor type 1 (CB1) and peripheral cannabinoid …

Recent advances in X-ray microtomography applied to materials

SR Stock - International materials reviews, 2008 - journals.sagepub.com
This review highlights recent advances in X-ray microcomputed tomography (microCT) as
applied to materials, specifically advances made since the first materials microCT review …

SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation

G Dobreva, M Chahrour, M Dautzenberg, L Chirivella… - Cell, 2006 - cell.com
Vertebrate skeletogenesis involves two processes, skeletal patterning and osteoblast
differentiation. Here, we show that Satb2, encoding a nuclear matrix protein, is expressed in …

In vivo small animal micro-CT using nanoparticle contrast agents

JR Ashton, JL West, CT Badea - Frontiers in pharmacology, 2015 - frontiersin.org
Computed tomography (CT) is one of the most valuable modalities for in vivo imaging
because it is fast, high-resolution, cost-effective, and non-invasive. Moreover, CT is heavily …

Micro-CT of rodents: state-of-the-art and future perspectives

DP Clark, CT Badea - Physica medica, 2014 - Elsevier
Micron-scale computed tomography (micro-CT) is an essential tool for phenotyping and for
elucidating diseases and their therapies. This work is focused on preclinical micro-CT …

Age‐and gender‐related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia

AJ Burghardt, GJ Kazakia… - Journal of Bone and …, 2010 - academic.oup.com
Cortical bone contributes the majority of overall bone mass and bears the bulk of axial loads
in the peripheral skeleton. Bone metabolic disorders often are manifested by cortical …

The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment

K Sawakami, AG Robling, M Ai, ND Pitner, D Liu… - Journal of Biological …, 2006 - ASBMB
The cell surface receptor, low-density lipoprotein receptor-related protein 5 (LRP5) is a key
regulator of bone mass. Loss-of-function mutations in LRP5 cause the human skeletal …