Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders
JA Jiménez, MJ Zylka - Journal of neurodevelopmental disorders, 2021 - Springer
Research with rodents is crucial for expanding our understanding of genetic and
environmental risk factors for neurodevelopmental disorders (NDD). However, there is …
environmental risk factors for neurodevelopmental disorders (NDD). However, there is …
Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring
Recent studies have suggested that physiological and behavioral traits may be
transgenerationally inherited through the paternal lineage, possibly via non-genomic signals …
transgenerationally inherited through the paternal lineage, possibly via non-genomic signals …
Mineralocorticoid and glucocorticoid receptor balance in control of HPA axis and behaviour
AP Harris, MC Holmes, ER De Kloet… - …, 2013 - Elsevier
An imbalance between central glucocorticoid (GR) and mineralocorticoid (MR) receptors is
proposed to underlie the HPA axis dysregulation that associates with susceptibility to …
proposed to underlie the HPA axis dysregulation that associates with susceptibility to …
Human gestational N‐methyl‐d‐aspartate receptor autoantibodies impair neonatal murine brain function
B Jurek, M Chayka, J Kreye, K Lang, L Kraus… - Annals of …, 2019 - Wiley Online Library
Objective Maternal autoantibodies are a risk factor for impaired brain development in
offspring. Antibodies (ABs) against the NR1 (GluN1) subunit of the N‐methyl‐d‐aspartate …
offspring. Antibodies (ABs) against the NR1 (GluN1) subunit of the N‐methyl‐d‐aspartate …
[HTML][HTML] Parenting behaviors in mice: olfactory mechanisms and features in models of autism spectrum disorders
A Dudas, TS Nakahara, LP Pellissier… - … & Biobehavioral Reviews, 2024 - Elsevier
Rodents, along with numerous other mammals, heavily depend on olfactory cues to
navigate their social interactions. Processing of olfactory sensory inputs is mediated by …
navigate their social interactions. Processing of olfactory sensory inputs is mediated by …
Direct and transgenerational effects of low doses of perinatal di-(2-ethylhexyl) phthalate (DEHP) on social behaviors in mice
KM Quinnies, EP Harris, RW Snyder, SS Sumner… - PLoS …, 2017 - journals.plos.org
Di-(2-ethylhexyl) phthalate (DEHP) is an endocrine disrupting chemical commonly used as a
plasticizer in medical equipment, food packaging, flooring, and children's toys. DEHP …
plasticizer in medical equipment, food packaging, flooring, and children's toys. DEHP …
Chronic psychosocial stress during pregnancy affects maternal behavior and neuroendocrine function and modulates hypothalamic CRH and nuclear steroid receptor …
SP Zoubovsky, S Hoseus, S Tumukuntala… - Translational …, 2020 - nature.com
Postpartum depression (PPD) affects up to 20% of mothers and has negative consequences
for both mother and child. Although exposure to psychosocial stress during pregnancy and …
for both mother and child. Although exposure to psychosocial stress during pregnancy and …
Enduring consequences of perinatal fentanyl exposure in mice
Opioid use by pregnant women is an understudied consequence associated with the opioid
epidemic, resulting in a rise in the incidence of neonatal opioid withdrawal syndrome …
epidemic, resulting in a rise in the incidence of neonatal opioid withdrawal syndrome …
Effects of maternal stress and perinatal fluoxetine exposure on behavioral outcomes of adult male offspring
V Kiryanova, SJ Meunier, HA Vecchiarelli, MN Hill… - Neuroscience, 2016 - Elsevier
Women of child-bearing age are the population group at highest risk for depression. In
pregnant women, fluoxetine (Flx) is the most widely prescribed selective serotonin reuptake …
pregnant women, fluoxetine (Flx) is the most widely prescribed selective serotonin reuptake …
Increased aggression, improved spatial memory, and reduced anxiety-like behaviour in adult male mice exposed to fluoxetine early in life
V Kiryanova, RH Dyck - Developmental neuroscience, 2014 - karger.com
Abstract Rationale: Fluoxetine (Flx; brand names Prozac, Sarafem, Rapiflux), a selective
serotonin reuptake inhibitor, is prescribed for the treatment of depression in pregnant …
serotonin reuptake inhibitor, is prescribed for the treatment of depression in pregnant …