HOTAIR: an oncogenic long non-coding RNA in human cancer

Q Tang, SS Hann - Cellular Physiology and Biochemistry, 2018 - karger.com
Abstract Long non-coding RNAs (LncRNAs) represent a novel class of noncoding RNAs that
are longer than 200 nucleotides without protein-coding potential and function as novel …

[HTML][HTML] The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer

ML Tornesello, R Faraonio, L Buonaguro… - Frontiers in …, 2020 - frontiersin.org
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …

Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides

KA Lennox, MA Behlke - Nucleic acids research, 2016 - academic.oup.com
Thousands of long non-coding RNAs (lncRNAs) have been identified in mammalian cells.
Some have important functions and their dysregulation can contribute to a variety of disease …

LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer

A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …

Functions of lncRNA HOTAIR in lung cancer

G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …

H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal …

E Zhang, L Han, D Yin, X He, L Hong, X Si… - Nucleic acids …, 2017 - academic.oup.com
Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …

[HTML][HTML] HOTAIR: an oncogenic long non-coding RNA in different cancers

M Hajjari, A Salavaty - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) refer to a group of RNAs that are usually more than 200
nucleotides and are not involved in protein generation. Instead, lncRNAs are involved in …

Circulating long non-coding RNAs in cancer: current status and future perspectives

P Qi, X Zhou, X Du - Molecular cancer, 2016 - Springer
Long non-coding RNAs (lncRNAs) comprise a diverse class of RNA transcripts> 200
nucleotides in length with limited protein-coding potential. In addition to their possible role in …

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

S Dhamija, S Diederichs - International journal of cancer, 2016 - Wiley Online Library
Metastasis is a multistep process that involves the dissemination of cells from the primary
tumor and colonization of distant secondary organs. Epithelial cells at the invasive front of a …

Expression of the long non-coding RNA HOTAIR correlates with disease progression in bladder cancer and is contained in bladder cancer patient urinary exosomes

C Berrondo, J Flax, V Kucherov, A Siebert, T Osinski… - PloS one, 2016 - journals.plos.org
Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from
biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA) …