The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …
physiological and pathological events in biology. Metal coordination chemistry, especially …
Changes in glutathione content in liver diseases: an update
Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …
thiol reducing agent involved in the modulation of redox processes. It has also been …
Connecting the chemical and biological properties of nitric oxide
JC Toledo Jr, O Augusto - Chemical research in toxicology, 2012 - ACS Publications
Nitric oxide (NO•; nitrogen monoxide) is known to be a critical regulator of cell and tissue
function through mechanisms that utilize its unique physicochemical properties as a small …
function through mechanisms that utilize its unique physicochemical properties as a small …
The comet assay in human biomonitoring: gene–environment interactions
M Dusinska, AR Collins - Mutagenesis, 2008 - academic.oup.com
The comet assay is the method of choice for measuring DNA damage, of various sorts, in
human cells such as lymphocytes obtained in the course of population-based studies of …
human cells such as lymphocytes obtained in the course of population-based studies of …
Glutathione transferases and development of new principles to overcome drug resistance
A Sau, FP Tregno, F Valentino, G Federici… - Archives of biochemistry …, 2010 - Elsevier
Chemoresistance is a multifactorial phenomenon and many studies clearly show that a
coordinated expression of efflux transporter proteins and phase II conjugating enzymes in …
coordinated expression of efflux transporter proteins and phase II conjugating enzymes in …
Dinitrosyl iron complexes with thiolate ligands: physico-chemistry, biochemistry and physiology
AF Vanin - Nitric oxide, 2009 - Elsevier
Some present-day concepts on the origin and functional activities of dinitrosyl iron
complexes (DNIC) with thiolate ligands are considered. Nitric oxide (NO) including to DNIC …
complexes (DNIC) with thiolate ligands are considered. Nitric oxide (NO) including to DNIC …
Glutathione, glutaredoxins, and iron
Significance: Glutathione (GSH) is the most abundant cellular low-molecular-weight thiol in
the majority of organisms in all kingdoms of life. Therefore, functions of GSH and disturbed …
the majority of organisms in all kingdoms of life. Therefore, functions of GSH and disturbed …
Cytoprotective and regulatory functions of glutathione S-transferases in cancer cell proliferation and cell death
S Singh - Cancer chemotherapy and pharmacology, 2015 - Springer
Abstract Purpose Glutathione S-transferases (GSTs) family of enzymes is best known for
their cytoprotective role and their involvement in the development of anticancer drug …
their cytoprotective role and their involvement in the development of anticancer drug …
[HTML][HTML] The good Samaritan glutathione-S-transferase P1: An evolving relationship in nitric oxide metabolism mediated by the direct interactions between multiple …
TM Russell, DR Richardson - Redox Biology, 2023 - Elsevier
Abstract Glutathione-S-transferases (GSTs) are phase II detoxification isozymes that
conjugate glutathione (GSH) to xenobiotics and also suppress redox stress. It was …
conjugate glutathione (GSH) to xenobiotics and also suppress redox stress. It was …
Nitrosyl iron complexes—synthesis, structure and biology
Nitrosyl complexes of iron are formed in living species in the presence of nitric oxide. They
are considered a form in which NO can be stored and stabilized within a living cell. Upon …
are considered a form in which NO can be stored and stabilized within a living cell. Upon …