ABSTRACT Growth differentiation factor 11 (GDF11) is a member of the transforming growth
factor-β superfamily that has garnered significant attention due to its anti-cardiac aging …

Aortic dissection (AD) is a cardiovascular disease that seriously endangers the lives of
patients. The mortality rate of this disease is high, and the incidence is increasing annually …

EuroSCORE II is one of the most widely utilized cardiovascular surgery risk scoring systems.
Recently, a new online score calculator, namely the German Registry of Acute Aortic …

ABSTRACT Background Cardiac adverse events (AEs) are common in tyrosine kinase
inhibitors (TKIs). This study explored the cardiac AEs of TKIs through the Food and Drug …

Background Extreme precipitation events are becoming more frequent due to climate
change. The present study aimed to explore the impacts of extreme precipitation on …

Increasing evidence shows that epigenetics also plays a key role in regulating the
pathogenetic mechanism of all types of aortic aneurysms. It is well-known that epigenetic …

Acute aortic dissection (AAD) and associated ruptures are the leading causes of death in
cardiovascular diseases (CVDs). Hypertension is a prime risk factor for AAD. However, the …

Abstract Estrogen receptor 1 (ESR1) has been recently demonstrated as a potential
diagnostic biomarker for thoracic aortic aneurysm (TAA). However, its precise role in the …

Thoracic aortic dissection (TAD) is a life-threatening vascular disease manifested as
intramural bleeding in the medial layers of the thoracic aorta. The key histopathologic …

Objective: The incidence of type B aortic dissection (TBAD) is increasing worldwide;
however, the underlying pathomechanisms are not conclusively understood. This study …