A new era of testosterone and prostate cancer: from physiology to clinical implications
M Khera, D Crawford, A Morales, A Salonia… - European urology, 2014 - Elsevier
Context Decades-old beliefs regarding androgens and prostate cancer (PCa) have
undergone dramatic shifts in light of modern evidence and new theoretical constructs, but …
undergone dramatic shifts in light of modern evidence and new theoretical constructs, but …
The relationship between total testosterone levels and prostate cancer: a review of the continuing controversy
J Klap, M Schmid, KR Loughlin - The Journal of urology, 2015 - Elsevier
Purpose For many years it was believed that higher total testosterone contributed to prostate
cancer and caused rapid cancer growth. International guidelines consider that adequate …
cancer and caused rapid cancer growth. International guidelines consider that adequate …
The biomarker sex hormone-binding globulin–from established applications to emerging trends in clinical medicine
MA Thaler, V Seifert-Klauss, PB Luppa - Best practice & research Clinical …, 2015 - Elsevier
Sex hormone-binding globulin (SHBG) is a serum glycoprotein exhibiting the unique feature
of binding sex steroids with high affinity and specificity. Its serum levels are regulated not …
of binding sex steroids with high affinity and specificity. Its serum levels are regulated not …
Superior biochemical recurrence and long-term quality-of-life outcomes are achievable with robotic radical prostatectomy after a long learning curve—updated …
JE Thompson, S Egger, M Böhm, AR Siriwardana… - European urology, 2018 - Elsevier
Background Our earlier analysis suggested that robot-assisted radical prostatectomy
(RARP) achieved superiority over open radical prostatectomy (ORP) in terms of positive …
(RARP) achieved superiority over open radical prostatectomy (ORP) in terms of positive …
Biomarker in active surveillance for prostate cancer: a systematic review
C Manceau, G Fromont, JB Beauval, E Barret… - Cancers, 2021 - mdpi.com
Simple Summary Recently, biomarkers have become a supplemental tool to aid in the
diagnosis and evaluation of prostate cancer. Numerous biomarkers are being developed …
diagnosis and evaluation of prostate cancer. Numerous biomarkers are being developed …
[HTML][HTML] Low serum total testosterone level as a predictor of upstaging and upgrading in low-risk prostate cancer patients meeting the inclusion criteria for active …
M Ferro, G Lucarelli, D Bruzzese, G Di Lorenzo… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Active surveillance (AS) is currently a widely accepted treatment option for men with
clinically localized prostate cancer (PCa). Several reports have highlighted the association …
clinically localized prostate cancer (PCa). Several reports have highlighted the association …
Biochemical recurrence after radical prostatectomy: Current status of its use as a treatment endpoint and early management strategies
BZ McCormick, AM Mahmoud, SB Williams… - Indian Journal of …, 2019 - journals.lww.com
Prostate cancer is one of the most common urological malignancies managed by a
practicing urologist. Treatment strategies are varied, but radical prostatectomy (RP) remains …
practicing urologist. Treatment strategies are varied, but radical prostatectomy (RP) remains …
Circulating preoperative testosterone level predicts unfavourable disease at radical prostatectomy in men with International Society of Urological Pathology Grade …
Purpose The association between circulating total testosterone (T) levels and clinically
significant PCa is still a matter of debate. In this study, we evaluated whether serum …
significant PCa is still a matter of debate. In this study, we evaluated whether serum …
Nuclear MTA1 overexpression is associated with aggressive prostate cancer, recurrence and metastasis in African Americans
Abstract Metastasis-associated protein 1 (MTA1), a negative epigenetic modifier, plays a
critical role in prostate cancer (PCa) progression. We hypothesized that MTA1 …
critical role in prostate cancer (PCa) progression. We hypothesized that MTA1 …
European Society for Sexual Medicine consensus statement on the use of the cavernous nerve injury rodent model to study postradical prostatectomy erectile …
Introduction Rodent animal models are currently the most used in vivo model in translational
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …
studies looking into the pathophysiology of erectile dysfunction after nerve-sparing radical …