Elevation of intraocular pressure (IOP) is a major risk factor for neurodegeneration in
glaucoma. Glial cells, which play an important role in normal functioning of retinal neurons …

Glaucoma is the second leading cause of blindness worldwide, affecting~ 80 million people
by 2020 (,). The condition is characterized by a progressive loss of retinal ganglion cells …

Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for
neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal …

Retinal ganglion cells, the neurons that die in glaucoma, are endowed with a high
metabolism requiring optimal provision of oxygen and nutrients to sustain their activity. The …

Glaucoma is a common optic neuropathy disease affecting over 76 million people. Both
timely diagnosis and progression monitoring are critical but challenging. Conventional …

Age-related macular degeneration is a common cause of blindless among the aged, which
can mainly be attributed to oxidative stress and dysregulated autophagy in retinal pigment …

Glaucoma is a chronic neurodegenerative disease characterized by apoptosis of retinal
ganglion cell (RGC) somas, degeneration of axons, and loss of synapses at dendrites and …

Glaucoma is a leading cause of blindness worldwide. In glaucoma, a progressive
dysfunction and death of retinal ganglion cells occurs, eliminating transfer of visual …

The retina is an extension of the central nervous system and has been considered to be a
simplified, more tractable and accessible version of the brain for a variety of neuroscience …

Glaucoma is the leading cause of irreversible blindness globally. The disease causes vision
loss due to neurodegeneration of the retinal ganglion cell (RGC) projection to the brain …