REPRODUCTION Page 1 REPRODUCTION REVIEW The role of BH3-only proteins in apoptosis
within the ovary Karla J Hutt1,2 1MIMR-PHI, Clayton, Victoria, Australia and 2Department of …

DRAM1 (DNA damage-regulated autophagy modulator 1) is a TP53 target gene that
modulates autophagy and apoptosis. We previously found that DRAM1 increased …

Abnormal ovarian function is the main manifestation of female reproductive toxicity.
Granulosa cells (GCs) play an important role in determining the fate of follicles and are the …

Advances in cancer therapy have focused attention on the quality of life of cancer survivors.
Since infertility is a major concern following chemotherapy, it is important to characterize the …

The aim of this study was to investigate effects of nitric oxide (NO) on steroidogenesis and
apoptosis in goat luteinized granulosa cells (LGCs). We cultured goat LGCs from healthy …

Sulphate contributes to numerous processes in mammalian physiology, particularly during
development. Sulphotransferases mediate the sulphate conjugation (sulphonation) of …

Ovarian granulosa cell tumors (GCTs) represent 3%–5% of all ovarian malignancies.
Treatments have limited proven efficacy and biologically targeted treatment is lacking. The …

Abstract Pou2F3 (POU class 2 homeobox 3) is found to be ubiquitously expressed in
multiple epidermal layer cells to mediating proliferation. Although some POU factors exert a …

El gen FMR1, responsable del Síndrome de Fragilidad del X (SFX), se localiza en el sitio
FRAXA en el brazo largo del cromosoma X (Xq27. 3), está compuesto por 17 exones …

Oocyte quality and the maintenance of the ovarian reserve are essential factors in
reproductive competence and fertility. The predominant portion of ovarian follicles are lost to …