Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Articular cartilage is a complex connective tissue with the fundamental functions of load
bearing, shock absorption and lubrication in joints. However, traumatic events, aging and …

Arthritis is a kind of chronic disease that affects joints and muscles with the symptoms of joint
pain, inflammation and limited movement of joints. Among various clinical therapies, drug …

Background The short-term safety and efficacy of stromal vascular fraction (SVF) in treating
knee osteoarthritis (KOA) have been extensively studied but the mid-term and long-term …

Objective Knee osteoarthritis (KOA) is a highly prevalent musculoskeletal disorder
characterized by degeneration of cartilage and abnormal remodeling of subchondral bone …

Force mapping of biological tissues via atomic force microscopy (AFM) probes the
mechanical properties of samples within a given topography, revealing the interplay …

In the context of a large animal model of early osteoarthritis (OA) treated by orthobiologics,
the purpose of this study was to reveal relations between articular tissues …

Objective Post-operative femoral shaft fractures are often accompanied by a residual
varus/valgus deformity, which can result in osteoarthritis in severe cases. The purpose of this …

Background Human adipose-derived stem cells (ADSCs) exert a strong anti-inflammatory
effect, and synovium-derived stem cells (SDSCs) have high chondrogenic potential. Thus …

The objective of this review is to systematically analyze the potential correlation between gut
microbiota and osteoarthritis (OA) as well as to evaluate the feasibility of microbiota-targeted …