[HTML][HTML] Inflammation as a central mechanism in Alzheimer's disease
JW Kinney, SM Bemiller, AS Murtishaw… - Alzheimer's & Dementia …, 2018 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …
Epidemiology of chronic effects of traumatic brain injury
J Haarbauer-Krupa, MJ Pugh, EM Prager… - Journal of …, 2021 - liebertpub.com
Although many patients diagnosed with traumatic brain injury (TBI), particularly mild TBI,
recover from their symptoms within a few weeks, a small but meaningful subset experience …
recover from their symptoms within a few weeks, a small but meaningful subset experience …
Role of ROS and RNS sources in physiological and pathological conditions
S Di Meo, TT Reed, P Venditti… - Oxidative medicine and …, 2016 - Wiley Online Library
There is significant evidence that, in living systems, free radicals and other reactive oxygen
and nitrogen species play a double role, because they can cause oxidative damage and …
and nitrogen species play a double role, because they can cause oxidative damage and …
Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia
NSN Graham, DJ Sharp - Journal of Neurology, Neurosurgery & …, 2019 - jnnp.bmj.com
Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer's
disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly …
disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly …
Geriatric traumatic brain injury: epidemiology, outcomes, knowledge gaps, and future directions
RC Gardner, K Dams-O'Connor… - Journal of …, 2018 - liebertpub.com
This review of the literature on traumatic brain injury (TBI) in older adults focuses on incident
TBI sustained in older adulthood (“geriatric TBI”) rather than on the separate, but related …
TBI sustained in older adulthood (“geriatric TBI”) rather than on the separate, but related …
[HTML][HTML] Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis
AC Bolte, AB Dutta, ME Hurt, I Smirnov… - Nature …, 2020 - nature.com
Traumatic brain injury (TBI) is a leading global cause of death and disability. Here we
demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause …
demonstrate in an experimental mouse model of TBI that mild forms of brain trauma cause …
Association of mild traumatic brain injury with and without loss of consciousness with dementia in US military veterans
DE Barnes, AL Byers, RC Gardner, KH Seal… - JAMA …, 2018 - jamanetwork.com
Importance Traumatic brain injury (TBI) is common in both veteran and civilian populations.
Prior studies have linked moderate and severe TBI with increased dementia risk, but the …
Prior studies have linked moderate and severe TBI with increased dementia risk, but the …
Epidemiology of mild traumatic brain injury and neurodegenerative disease
RC Gardner, K Yaffe - Molecular and Cellular Neuroscience, 2015 - Elsevier
Every year an estimated 42 million people worldwide suffer a mild traumatic brain injury
(MTBI) or concussion. More severe traumatic brain injury (TBI) is a well-established risk …
(MTBI) or concussion. More severe traumatic brain injury (TBI) is a well-established risk …
Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …
Risk factors associated with the onset and progression of Alzheimer's disease: A systematic review of the evidence
M Hersi, B Irvine, P Gupta, J Gomes, N Birkett… - Neurotoxicology, 2017 - Elsevier
A systematic review was conducted to identify risk factors associated with the onset and
progression of Alzheimer's disease (AD). Moderate and high quality systematic reviews …
progression of Alzheimer's disease (AD). Moderate and high quality systematic reviews …