The natural mammalian polyamines putrescine, spermidine and spermine are essential for
both normal and neoplastic cell function and replication. Dysregulation of metabolism of …

Aging involves the systemic deterioration of all known cell types in most eukaryotes. Several
recently discovered compounds that extend the healthspan and lifespan of model organisms …

Obesity is associated with impaired intestinal barrier function and dysbiosis of the gut
microbiota. Spermidine, a polyamine that acts as an autophagy inducer, has important …

The polyamines putrescine, spermidine, and spermine are abundant polycations of vital
importance in mammalian cells. Their cellular levels are tightly regulated by degradation …

Spermidine is a natural polyamine that has health benefits and extends life span in several
species. Deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH) are key …

Biogenic amines (BAs) can be found in a wide range of meat and meat products, where they
are important as an index for product stability and quality, but also for their impact on public …

Infant formulas are an alternative to replace or supplement human milk when breastfeeding
is not possible. The knowledge of human milk's bioactive compounds and their beneficial …

Miso is a well‐known traditional Japanese fermented food, with a characteristic savory flavor
and aroma, known predominately as the seasoning in miso soup. Miso production involves …

Background The cross-talk between the host and its microbiota plays a key role in the
promotion of health. The production of metabolites such as polyamines by intestinal-resident …

As human life expectancy is rising, the incidence of age-associated diseases will also
increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins …