Steatosis in liver transplantation: current limitations and future strategies
In parallel with the pandemic of obesity and diabetes, the prevalence of nonalcoholic fatty
liver disease has progressively increased. Nonalcoholic steatohepatitis (NASH), a subtype …
liver disease has progressively increased. Nonalcoholic steatohepatitis (NASH), a subtype …
miR-124-3p delivered by exosomes from heme oxygenase-1 modified bone marrow mesenchymal stem cells inhibits ferroptosis to attenuate ischemia–reperfusion …
L Wu, X Tian, H Zuo, W Zheng, X Li, M Yuan… - Journal of …, 2022 - Springer
Background Steatotic livers tolerate ischemia–reperfusion injury (IRI) poorly, increasing the
risk of organ dysfunction. Ferroptosis is considered the initiating factor of organ IRI. Heme …
risk of organ dysfunction. Ferroptosis is considered the initiating factor of organ IRI. Heme …
Changing trends in liver transplantation: challenges and solutions
Despite improvements in postliver transplant outcomes through refinements in perioperative
management and surgical techniques, several changing trends in liver transplantation have …
management and surgical techniques, several changing trends in liver transplantation have …
Primary nonfunction of the liver allograft
H Hartog, A Hann, MTPR Perera - Transplantation, 2022 - journals.lww.com
Severe allograft dysfunction, as opposed to the expected immediate function, following liver
transplantation is a major complication, and the clinical manifestations of such that lead to …
transplantation is a major complication, and the clinical manifestations of such that lead to …
[HTML][HTML] The impact of postreperfusion syndrome during liver transplantation using livers with significant macrosteatosis
The impact of postreperfusion syndrome (PRS) during liver transplantation (LT) using donor
livers with significant macrosteatosis is largely unknown. Clinical outcomes of all patients …
livers with significant macrosteatosis is largely unknown. Clinical outcomes of all patients …
Role of endoplasmic reticulum stress in hepatic glucose and lipid metabolism and therapeutic strategies for metabolic liver disease
W Zheng, Q Sun, L Li, Y Cheng, Y Chen, M Lv… - International …, 2022 - Elsevier
The endoplasmic reticulum is the most abundant membrane organelle in eukaryotic cells. It
is an important site of membrane and secretory protein folding and glycolipid synthesis and …
is an important site of membrane and secretory protein folding and glycolipid synthesis and …
[PDF][PDF] The “skinny” on assessment and utilization of steatotic liver grafts: a systematic review
The frequency at which steatotic deceased donor liver grafts are encountered will likely
continue to increase. Utilization of liver grafts with moderate‐to‐severe steatosis for liver …
continue to increase. Utilization of liver grafts with moderate‐to‐severe steatosis for liver …
Fully automated quantitative assessment of hepatic steatosis in liver transplants
Background The presence of macro-and microvesicular steatosis is one of the major risk
factors for liver transplantation. An accurate assessment of the steatosis percentage is …
factors for liver transplantation. An accurate assessment of the steatosis percentage is …
The impact of steatosis on the outcome of liver transplantation: a meta‐analysis
QY Zhang, QF Zhang, DZ Zhang - BioMed research …, 2019 - Wiley Online Library
Background and Aims. Liver transplantation is one of the most effective treatments for end‐
stage liver disease as well as for cases of acute liver failure. Facing organ donor shortage …
stage liver disease as well as for cases of acute liver failure. Facing organ donor shortage …
Fluorescence confocal microscopy on liver specimens for full digitization of transplant pathology
MN Kinzler, F Schulze, A Reitz, S Gretser… - Liver …, 2023 - journals.lww.com
Fluorescence confocal microscopy (FCM) is a rapidly evolving tool that provides real-time
virtual HE images of native tissue. Data about the potential of FCM as an alternative to …
virtual HE images of native tissue. Data about the potential of FCM as an alternative to …