Numerous intrinsic currents are known to collectively shape neuronal membrane potential
dynamics, or neuronal signatures. Although how sets of currents shape specific signatures …

Parameter tuning of model neurons to mimic biologically realistic activity is a non‐trivial task.
Multiple models may exhibit similar dynamics that match experimental data–ie, there is no …

We have recently created the world's largest biologically plausible brain model that is
capable of performing several perceptual, motor, and cognitive tasks (Eliasmith et al., 2012) …