Natural withanolides, an update
G Xia, S Cao, L Chen, F Qiu - Natural Product Reports, 2022 - pubs.rsc.org
Covering: March 2010 to December 2020. Previous review: Nat. Prod. Rep., 2011, 28, 705
This review summarizes the latest progress and perspectives on the structural classification …
This review summarizes the latest progress and perspectives on the structural classification …
[HTML][HTML] Functional expression and regulation of eukaryotic cytochrome P450 enzymes in surrogate microbial cell factories
P Durairaj, S Li - Engineering Microbiology, 2022 - Elsevier
Cytochrome P450 (CYP) enzymes play crucial roles during the evolution and diversification
of ancestral monocellular eukaryotes into multicellular eukaryotic organisms due to their …
of ancestral monocellular eukaryotes into multicellular eukaryotic organisms due to their …
A Decade of Molecular Understanding of Withanolide Biosynthesis and In vitro Studies in Withania somnifera (L.) Dunal: Prospects and Perspectives for Pathway …
Withania somnifera, a multipurpose medicinal plant is a rich reservoir of pharmaceutically
active triterpenoids that are steroidal lactones known as withanolides. Though the plant has …
active triterpenoids that are steroidal lactones known as withanolides. Though the plant has …
[HTML][HTML] The integration of metabolomics and next-generation sequencing data to elucidate the pathways of natural product metabolism in medicinal plants
Plants have always been used as medicines since ancient times to treat diseases. The
knowledge around the active components of herbal preparations has remained …
knowledge around the active components of herbal preparations has remained …
Functional characterization of Cinnamate 4-hydroxylase gene family in soybean (Glycine max)
Cinnamate 4-hydroxylase (C4H) is the first key cytochrome P450 monooxygenase (P450)
enzyme in the phenylpropanoid pathway. It belongs to the CYP73 family of P450 …
enzyme in the phenylpropanoid pathway. It belongs to the CYP73 family of P450 …
Cloning and functional characterization of three branch point oxidosqualene cyclases from Withania somnifera (L.) dunal
Oxidosqualene cyclases (OSCs) positioned at a key metabolic subdividing junction execute
indispensable enzymatic cyclization of 2, 3-oxidosqualene for varied triterpenoid …
indispensable enzymatic cyclization of 2, 3-oxidosqualene for varied triterpenoid …
Rheum australe, an endangered high-value medicinal herb of North Western Himalayas: a review of its botany, ethnomedical uses, phytochemistry and …
SA Pandith, RA Dar, SK Lattoo, MA Shah… - Phytochemistry …, 2018 - Springer
Abstract Rheum australe (Himalayan Rhubarb) is a multipurpose, endemic and endangered
medicinal herb of North Western Himalayas. It finds extensive use as a medicinal herb since …
medicinal herb of North Western Himalayas. It finds extensive use as a medicinal herb since …
Biotechnological interventions in Withania somnifera (L.) Dunal
Withania somnifera is one of the most valued plants and is extensively used in Indian,
Unani, and African systems of traditional medicine. It possess a wide array of therapeutic …
Unani, and African systems of traditional medicine. It possess a wide array of therapeutic …
Jasmonate responsive transcription factor WsMYC2 regulates the biosynthesis of triterpenoid withanolides and phytosterol via key pathway genes in Withania …
Key message Functional characterization of Ws MYC2 via artificial microRNA mediated
silencing and transient over-expression displayed significant regulatory role vis-à-vis …
silencing and transient over-expression displayed significant regulatory role vis-à-vis …
Class II cytochrome P450 reductase governs the biosynthesis of alkaloids
C Parage, E Foureau, F Kellner, V Burlat… - Plant …, 2016 - academic.oup.com
Expansion of the biosynthesis of plant specialized metabolites notably results from the
massive recruitment of cytochrome P450s that catalyze multiple types of conversion of …
massive recruitment of cytochrome P450s that catalyze multiple types of conversion of …