Effects of codon optimization on the mRNA levels of heterologous genes in filamentous fungi

M Tanaka, M Tokuoka, K Gomi - Applied microbiology and biotechnology, 2014 - Springer
Filamentous fungi, particularly Aspergillus species, have recently attracted attention as host
organisms for recombinant protein production. Because the secretory yields of heterologous …

Comprehensive Analysis of Codon Usage Bias in Seven Epichloë Species and Their Peramine-Coding Genes

H Song, J Liu, Q Song, Q Zhang, P Tian… - Frontiers in …, 2017 - frontiersin.org
Codon usage bias plays an important role in shaping genomes and genes in unicellular
species and multicellular species. Here, we first analyzed codon usage bias in seven …

Visualized Multigene Editing System for Aspergillus niger

C Li, J Zhou, S Rao, G Du, S Liu - ACS Synthetic Biology, 2021 - ACS Publications
The resistance markers could ensure the entry of the CRISPR/Cas9 system into Aspergillus
niger cells instead of gene editing. To increase the efficiency of positive colony screening on …

Comparative study of codon usage profiles of Zingiber officinale and its associated fungal pathogens

S Gupta, R Singh - Molecular Genetics and Genomics, 2021 - Springer
Codon usage bias influences the genetic features prevalent in genomes of all the
organisms. It also plays a crucial role in establishing the host–pathogen relationship. The …

Biosynthesis of the Pharmaceutically Important Fungal Ergot Alkaloid Dihydrolysergic Acid Requires a Specialized Allele of cloA

SL Arnold, DG Panaccione - Applied and Environmental …, 2017 - Am Soc Microbiol
Ergot alkaloids are specialized fungal metabolites that are important as the bases of several
pharmaceuticals. Many ergot alkaloids are derivatives of lysergic acid (LA) and have …

Codon usage in the flatworm Schistosoma mansoni is shaped by the mutational bias towards a+ T and translational selection, which increases GC-ending codons in …

G Lamolle, A Iriarte, H Musto - Molecular and Biochemical Parasitology, 2022 - Elsevier
Schistosoma mansoni is a trematode flatworm that parasitizes humans and produces a
disease called bilharzia. At the genomic level, it is characterized by a low genomic GC …

[HTML][HTML] Codon usage signatures in the genus Cryptococcus: a complex interplay of gene expression, translational selection and compositional bias

S Gupta, K Paul, A Roy - Genomics, 2021 - Elsevier
The fungal genus Cryptococcus comprises of several diverse species. The pathogens
forming Cryptococcus neoformans/Cryptococcus gatti species complex are of immense …

Comprehensive profiling of codon usage signatures and codon context variations in the genus Ustilago

A Roy, J van Staden - World Journal of Microbiology and Biotechnology, 2019 - Springer
The fungal genus Ustilago consists of intimidating pathogens associated with disease
manifestations in plants of agricultural importance and gravity. Rapid progress of genome …

Insights into the riddles of codon usage patterns and codon context signatures in fungal genus Puccinia, a persistent threat to global agriculture

A Roy, J van Staden - Journal of Cellular Biochemistry, 2019 - Wiley Online Library
The fungal genus Puccinia, comprising of several menacing pathogens, has been a
persistent peril to global agriculture. Genome sequencing of various members of Puccinia …

The complex pattern of codon usage evolution in the family Comamonadaceae

E Jara, MA Morel, G Lamolle, S Castro-Sowinski… - Ecological Genetics and …, 2018 - Elsevier
The family Comamonadaceae belongs to the Beta subdivision of the phylum Proteobacteria.
Members of this family display differential biological properties, mainly related to …