[HTML][HTML] Curcumin combination chemotherapy: The implication and efficacy in cancer

BL Tan, ME Norhaizan - Molecules, 2019 - mdpi.com
Many chemotherapeutic drugs have been used for the treatment of cancer, for instance,
doxorubicin, irinotecan, 5-fluorouracil, cisplatin, and paclitaxel. However, the effectiveness of …

[HTML][HTML] Advancements in rectal drug delivery systems: clinical trials, and patents perspective

R Rathi, Sanshita, A Kumar, V Vishvakarma… - Pharmaceutics, 2022 - mdpi.com
The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …

pH/ROS dual-sensitive and chondroitin sulfate wrapped poly (β-amino ester)-SA-PAPE copolymer nanoparticles for macrophage-targeted oral therapy for ulcerative …

H Xu, R Luo, L Dong, X Pu, Q Chen, N Ye, S Qi… - … , Biology and Medicine, 2022 - Elsevier
An oral nanoparticle (NPs) encapsulated in chitosan/alginate hydrogel (CA-Gel) with dual-
sensitive in pH and reactive oxygen species (ROS) was developed to load curcumin (CUR) …

Curcumin-based nanotechnology approaches and therapeutics in restoration of autoimmune diseases

N Rahiman, YV Markina, P Kesharwani… - Journal of Controlled …, 2022 - Elsevier
Autoimmune diseases usually arise as a result of an aberrant immune system attack on
normal tissues of the body, which leads to a cascade of inflammatory reactions. The immune …

Genipin-crosslinked human serum albumin coating using a tannic acid layer for enhanced oral administration of curcumin in the treatment of ulcerative colitis

R Luo, M Lin, C Zhang, J Shi, S Zhang, Q Chen, Y Hu… - Food chemistry, 2020 - Elsevier
Curcumin (CUR) is a promising edible phytochemical compound with ideal ulcerative colitis
(UC) treatment activity; however, it is characteristically instable in the digestive tract and has …

Glucans and applications in drug delivery

H Lin, R Han, W Wu - Carbohydrate Polymers, 2024 - Elsevier
Glucan is a natural polysaccharide widely distributed in cereals and microorganisms that
has various biological activities, including immunomodulatory, anti-infective, anti …

Nanocarriers based on vitamin E-TPGS: Design principle and molecular insights into improving the efficacy of anticancer drugs

S Rathod, P Bahadur, S Tiwari - International Journal of Pharmaceutics, 2021 - Elsevier
Abstract α-Tocopheryl polyethylene glycol succinate (vitamin E-TPGS or TPGS) is a nonionic
amphiphile synthesized by the esterification of vitamin E succinate. It has been categorized …

Curcumin formulated in solid lipid nanoparticles has enhanced efficacy in Hodgkin's lymphoma in mice

J Guorgui, R Wang, G Mattheolabakis… - Archives of biochemistry …, 2018 - Elsevier
Curcumin reduces Hodgkin's lymphoma (HL) cell growth in vitro, but its unfavorable
pharmacokinetics highlight the need for novel in vivo delivery systems. Thus, we explored …

Tocophersolan stabilized lipid nanocapsules with high drug loading to improve the permeability and oral bioavailability of curcumin

P Bapat, R Ghadi, D Chaudhari, SS Katiyar… - International journal of …, 2019 - Elsevier
The present investigation highlights the development of D-α-Tocopheryl polyethylene glycol
1000 succinate (Tocophersolan; TPGS) stabilized lipid nanocapsules for enhancing the oral …

Curcuminoids from Curcuma Longa: New adjuvants for the treatment of crohn's disease and ulcerative colitis?

F Cunha Neto, LT Marton, SV de Marqui… - Critical reviews in …, 2019 - Taylor & Francis
Crohn's Disease (CD) and Ulcerative Colitis (UC) result from an overreaction of the bowel to
multifactorial stimuli leading to discomfort, pain, and it is associated with high morbidity and …