Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

Cell models and their application for studying adipogenic differentiation in relation to obesity: a review

FJ Ruiz-Ojeda, AI Rupérez, C Gomez-Llorente… - International journal of …, 2016 - mdpi.com
Over the last several years, the increasing prevalence of obesity has favored an intense
study of adipose tissue biology and the precise mechanisms involved in adipocyte …

Environmental metabolomics: an emerging approach to study organism responses to environmental stressors

BP Lankadurai, EG Nagato… - Environmental …, 2013 - cdnsciencepub.com
Metabolomics is the analysis of endogenous and exogenous low molecular mass
metabolites within a cell, tissue, or biofluid of an organism in response to an external …

The endocrine disruptor mono-(2-ethylhexyl) phthalate promotes adipocyte differentiation and induces obesity in mice

C Hao, X Cheng, H Xia, X Ma - Bioscience reports, 2012 - portlandpress.com
The environmental obesogen hypothesis proposes that exposure to endocrine disruptors
during developmental 'window'contributes to adipogenesis and the development of obesity …

Obesogenic endocrine disrupting chemicals: identifying knowledge gaps

A Veiga-Lopez, Y Pu, J Gingrich… - Trends in Endocrinology & …, 2018 - cell.com
Endocrine disrupting chemicals (EDCs) are compounds that are part of everyday consumer
products and industrial manufacturing processes. EDCs can interfere with the endocrine …

Obesogens: How they are identified and molecular mechanisms underlying their action

N Mohajer, CY Du, C Checkcinco… - Frontiers in …, 2021 - frontiersin.org
Adult and childhood obesity have reached pandemic level proportions. The idea that caloric
excess and insufficient levels of physical activity leads to obesity is a commonly accepted …

Exposure to endocrine-disrupting compounds such as phthalates and bisphenol A is associated with an increased risk for obesity

R Biemann, M Blüher, B Isermann - Best Practice & Research Clinical …, 2021 - Elsevier
Increasing evidence from epidemiological, animal and in vitro studies suggests that the
increased production of synthetic chemicals that interfere with the proper functioning of the …

[HTML][HTML] Phthalate exposure and childhood overweight and obesity: Urinary metabolomic evidence

B Xia, Q Zhu, Y Zhao, W Ge, Y Zhao, Q Song… - Environment …, 2018 - Elsevier
Objective Metabolomics may unravel global metabolic changes in response to
environmental exposures and identify important biological pathways involved in the …

The role of persistent organic pollutants in obesity: a review of laboratory and epidemiological studies

J Aaseth, D Javorac, AB Djordjevic, Z Bulat, AV Skalny… - Toxics, 2022 - mdpi.com
Persistent organic pollutants (POPs) are considered as potential obesogens that may affect
adipose tissue development and functioning, thus promoting obesity. However, various …