The regulation of endocrine-disrupting chemicals to minimize their impact on health

C Duh-Leong, MV Maffini, CD Kassotis… - Nature Reviews …, 2023 - nature.com
Endocrine-disrupting chemicals (EDCs) are substances generated by human industrial
activities that are detrimental to human health through their effects on the endocrine system …

Endocrine-disrupting chemicals and child health

A Ghassabian, L Vandenberg, K Kannan… - Annual review of …, 2022 - annualreviews.org
While definitions vary, endocrine-disrupting chemicals (EDCs) have two fundamental
features: their disruption of hormone function and their contribution to disease and disability …

The Florence statement on triclosan and triclocarban

RU Halden, AE Lindeman, AE Aiello… - Environmental …, 2017 - ehp.niehs.nih.gov
The Florence Statement on Triclosan and Triclocarban documents a consensus of more
than 200 scientists and medical professionals on the hazards of and lack of demonstrated …

Endocrine disruptors and the future of toxicology testing—lessons from CLARITY–BPA

LN Vandenberg, PA Hunt, AC Gore - Nature reviews endocrinology, 2019 - nature.com
Five years ago, an ambitious collaboration, the Consortium Linking Academic and
Regulatory Insights on Toxicity of BPA (CLARITY–BPA; henceforth CLARITY), was launched …

Understanding the correlation between in vitro and in vivo immunotoxicity tests for nanomedicines

MA Dobrovolskaia, SE McNeil - Journal of controlled release, 2013 - Elsevier
Preclinical characterization of novel nanotechnology-based formulations is often challenged
by physicochemical characteristics, sterility/sterilization issues, safety and efficacy. Such …

Addressing systemic problems with exposure assessments to protect the public's health

LN Vandenberg, SDG Rayasam, DA Axelrad… - Environmental …, 2023 - Springer
Background Understanding, characterizing, and quantifying human exposures to
environmental chemicals is critical to protect public health. Exposure assessments are key to …

Improving and expanding estimates of the global burden of disease due to environmental health risk factors

RM Shaffer, SP Sellers, MG Baker… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: The Global Burden of Disease (GBD) study, coordinated by the Institute for
Health Metrics and Evaluation (IHME), produces influential, data-driven estimates of the …

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in …

I Moffat, NL Chepelev, S Labib… - Critical reviews in …, 2015 - Taylor & Francis
Toxicogenomics is proposed to be a useful tool in human health risk assessment. However,
a systematic comparison of traditional risk assessment approaches with those applying …

Endocrine disruptor chemicals and children's health

G Di Pietro, F Forcucci, F Chiarelli - International Journal of Molecular …, 2023 - mdpi.com
We are all exposed to endocrine-disrupting chemicals (EDCs) starting from embryonic life.
The fetus and child set up crucial developmental processes allowing adaptation to the …

Application of the Navigation Guide systematic review methodology to the evidence for developmental and reproductive toxicity of triclosan

PI Johnson, E Koustas, HM Vesterinen, P Sutton… - Environment …, 2016 - Elsevier
Background There are reports of developmental and reproductive health effects associated
with the widely used biocide triclosan. Objective Apply the Navigation Guide systematic …