[HTML][HTML] Mechanical stimulation improves rotator cuff tendon-bone healing via activating IL-4/JAK/STAT signaling pathway mediated macrophage M2 polarization

Y Liu, L Wang, S Li, T Zhang, C Chen, J Hu… - Journal of Orthopaedic …, 2022 - Elsevier
Background It is well known that appropriate mechanical stimulation benefits tendon-bone
(TB) healing, however, the mechanisms behind this are still uncovered completely. Here, we …

Review of human supraspinatus tendon mechanics. Part II: tendon healing response and characterization of tendon health

KM Griffith, LC Hammer, NP Iannuzzi… - Journal of shoulder and …, 2022 - Elsevier
Overuse injuries of the rotator cuff, particularly of the supraspinatus tendon (SST), are highly
prevalent and debilitating in work, sport, and daily activities. Despite the clinical significance …

Effect of mechanical stimulation combined with platelet-rich plasma on healing of the rotator cuff in a murine model

Y Peng, X Li, W Wu, H Ma, G Wang… - … American Journal of …, 2022 - journals.sagepub.com
Background: Mechanical stimulation and platelet-rich plasma (PRP) have been shown to be
beneficial for healing of the bone-tendon interface (BTI), but few studies have explored the …

[HTML][HTML] Early treadmill running delays rotator cuff healing via Neuropeptide Y mediated inactivation of the Wnt/β-catenin signaling

Y Chen, T Zhang, L Wan, Z Wang, S Li, J Hu… - Journal of Orthopaedic …, 2021 - Elsevier
Background Defining the optimal rehabilitation programs for rotator cuff healing remains a
challenge. Early treadmill running may have negative effects on tendon-bone interface (TBI) …

Current Evidence Based Recommendations on Rehabilitation following Arthroscopic Shoulder Surgery: Rotator Cuff, Instability, Superior Labral Pathology, and …

J Corban, S Shah, AJ Ramappa - Current Reviews in Musculoskeletal …, 2024 - Springer
Abstract Purpose of Review Arthroscopy has become increasingly popular for a addressing
a wide variety of shoulder pathology. However, despite increasing interest, there is still much …

Mechanical stimulation promotes enthesis injury repair by mobilizing Prrx1+ cells via ciliary TGF-β signaling

H Xiao, T Zhang, C Li, Y Cao, L Wang, H Chen, S Li… - Elife, 2022 - elifesciences.org
Proper mechanical stimulation can improve rotator cuff enthesis injury repair. However, the
underlying mechanism of mechanical stimulation promoting injury repair is still unknown. In …

Effect of exercise intensity on the healing of the bone-tendon interface: a mouse rotator cuff injury model study

H Chen, S Li, H Xiao, B Wu, L Zhou… - The American Journal …, 2021 - journals.sagepub.com
Background: Injuries at the bone-tendon interface (BTI) are common findings in clinical
practice. Rehabilitation procedures after BTI surgery are important but are controversial …

Treadmill exercise facilitated rotator cuff healing is coupled with regulating periphery neuropeptides expression in a murine model

T Zhang, Y Chen, C Chen, S Li, H Xiao… - Journal of …, 2021 - Wiley Online Library
Postoperative exercise has been found able to accelerate bone‐tendon (B‐T) healing. In
this study, we systematically compared tendon‐to‐bone healing in mice subjected to …

Extracellular C1qbp inhibits myogenesis by suppressing NFATc1

JM Kim, HK Kim, HJ Cho, SA Moon, Y Kim, JY Hong… - Scientific Reports, 2024 - nature.com
Aging and lack of exercise are the most important etiological factors for muscle loss. We
hypothesized that new factors that contribute to muscle loss could be identified from ones …

The role of Indian hedgehog signaling in tendon response to subacromial impingement: evaluation using a mouse model

Y Liu, XH Deng, X Zhang, T Cong… - … American Journal of …, 2022 - journals.sagepub.com
Background: The underlying cellular and molecular mechanisms involved in the
development of tendinopathy due to subacromial supraspinatus tendon (SST) impingement …