Ebselen and analogues: Pharmacological properties and synthetic strategies for their preparation
C Santi, C Scimmi, L Sancineto - Molecules, 2021 - mdpi.com
Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …
Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways
GK Azad, RS Tomar - Molecular biology reports, 2014 - Springer
Ebselen, an organoselenium compound, mimics glutathione peroxidase activity. It is a
multifunctional compound, which catalyzes several essential reactions for the protection of …
multifunctional compound, which catalyzes several essential reactions for the protection of …
Organoselenium compounds as mimics of selenoproteins and thiol modifier agents
Selenium is an essential trace element for animals and its role in the chemistry of life relies
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …
on a unique functional group: the selenol (–SeH) group. The selenol group participates in …
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
Proteases encoded by SARS-CoV-2 constitute a promising target for new therapies against
COVID-19. SARS-CoV-2 main protease (Mpro, 3CLpro) and papain-like protease (PLpro) …
COVID-19. SARS-CoV-2 main protease (Mpro, 3CLpro) and papain-like protease (PLpro) …
Tetravalent Spiroselenurane Catalysts: Intramolecular Se···N Chalcogen Bond-Driven Catalytic Disproportionation of H2O2 to H2O and O2 and Activation of I2 and …
Chalcogen-bonding interactions have recently gained considerable attention in the field of
synthetic chemistry, structure, and bonding. Here, three organo-spiroselenuranes, having a …
synthetic chemistry, structure, and bonding. Here, three organo-spiroselenuranes, having a …
Directing Group Strategy for the Isolation of Organoselenium (VI) Benzoselenonates: Metal-Free Catalysts for Hydrogen Evolution Reaction
The exploration of fourth-period organoelements, particularly organoseleniums in their
highest VI oxidation state, is limited owing to their stability and synthesis. Herein, the …
highest VI oxidation state, is limited owing to their stability and synthesis. Herein, the …
CuBr2-Catalyzed Annulation of 2-Bromo-N-Arylbenzimidamide with Se/S8 Powder for the Synthesis of Benzo[d]isoselenazole and Benzo[d]isothiazole
Q Wang, F Xiao, Z Huang, G Mao… - The Journal of Organic …, 2023 - ACS Publications
A CuBr2-catalyzed annulation of 2-bromo-N-arylbenzimidamide with selenium/sulfur
powder for the synthesis of benzo [d] isoselenazole and benzo [d] isothiazole in generally …
powder for the synthesis of benzo [d] isoselenazole and benzo [d] isothiazole in generally …
2‐Benzamide Tellurenyl Iodides: Synthesis and Their Catalytic Role in CO2 Mitigation
Benzamide‐derived organochalcogens (chalcogen= S, Se, and Te) have shown promising
interest in biological and synthetic chemistry. Ebselen molecule derived from benzamide …
interest in biological and synthetic chemistry. Ebselen molecule derived from benzamide …
Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (Mpro) of Severe Acute Respiratory Syndrome Coronavirus-2 …
SARS-CoV-2 main protease (Mpro/3CLpro) is a crucial target for therapeutics, which is
responsible for viral polyprotein cleavage and plays a vital role in virus replication and …
responsible for viral polyprotein cleavage and plays a vital role in virus replication and …
Metal‐Free Synthesis of Aryl Selenocyanates and Selenaheterocycles with Elemental Selenium
X Zhang, XB Huang, YB Zhou, MC Liu… - … –A European Journal, 2021 - Wiley Online Library
This work reports a green method for the synthesis of aryl selenocyanates via a three‐
component reaction of arylboronic acids, Se powder, and trimethylsilyl cyanide (TMSCN) …
component reaction of arylboronic acids, Se powder, and trimethylsilyl cyanide (TMSCN) …