It has long been hypothesized that conditioning mechanisms play major roles in addiction.
Specifically, the associations between rewarding properties of drugs of abuse and the drug …

Alcoholism results from an interplay between genetic and environmental factors, and is
linked to brain defects and associated cognitive, emotional, and behavioral impairments. A …

The cognitive repercussions of alcohol dependence are well documented. However, the
literature remains somewhat ambiguous with respect to which distinct cognitive functions are …

Neurocognitive impairments are prevalent in persons seeking treatment for alcohol use
disorders (AUDs). These impairments and their physical, social, psychological and …

Long-term chronic alcoholism is associated with disparate and widespread residual
consequences for brain functioning and behavior, and alcoholics suffer a variety of cognitive …

Animal and human laboratory paradigms offer invaluable approaches to study the complex
etiologies and mechanisms of alcohol use disorder (AUD). We contend that human …

Background: Chronic alcoholism is known to impair episodic memory function, but the
specific nature of this impairment is still unclear. Moreover, it has never been established …

Over the past 40 years, rigorous examination of brain function, structure, and attending
factors through multidisciplinary research has helped identify the substrates of alcohol …

The mediodorsal nuclei of thalamus (MD), prefrontal cortex (PFC), and nucleus accumbens
core (NAc) form an interconnected network that may work together to subserve certain forms …

Objective: To examine the association between alcohol use and cognitive decline in a
longitudinal study of a representative elderly community sample free of dementia at …