Formononetin: a review of its anticancer potentials and mechanisms

KC Tay, LTH Tan, CK Chan, SL Hong… - Frontiers in …, 2019 - frontiersin.org
Cancer, a complex yet common disease, is caused by uncontrolled cell division and
abnormal cell growth due to a variety of gene mutations. Seeking effective treatments for …

The emerging roles of exosomes as EMT regulators in cancer

H Kim, S Lee, E Shin, KM Seong, YW Jin, HS Youn… - Cells, 2020 - mdpi.com
Epithelial–mesenchymal transition (EMT) causes epithelial cells to lose their polarity and
adhesion property, and endows them with migratory and invasive properties to enable them …

Retracted: Mettl14 suppresses crc progression Via regulating N6-Methyladenosine-Dependent primary mir-375 processing

X Chen, M Xu, X Xu, K Zeng, X Liu, L Sun, B Pan, B He… - Molecular Therapy, 2020 - cell.com
Epigenetic alterations contributed to human carcinogenesis immensely. N6-
methyladenosine (m6A) is one of the most preventive and abundant modifications on RNA …

circKIF4A acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer

H Tang, X Huang, J Wang, L Yang, Y Kong, G Gao… - Molecular cancer, 2019 - Springer
Background Increasing studies has found that circular RNAs (circRNAs) play vital roles in
cancer progression. But the expression profile and function of circRNAs in triple-negative …

Novel antitumor therapeutic strategy using CD4+ T cell-derived extracellular vesicles

S Shin, I Jung, D Jung, CS Kim, SM Kang, S Ryu… - Biomaterials, 2022 - Elsevier
Extracellular vesicles (EVs) mediate cell-cell crosstalk by carrying bioactive molecules
derived from cells. Recently, immune cell-derived EVs have been reported to regulate key …

miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis

W Kang, T Huang, Y Zhou, J Zhang, RWM Lung… - Cell death & …, 2018 - nature.com
Abstract miR-375 is a tumor-suppressive microRNA (miRNA) in gastric cancer (GC).
However, its molecular mechanism remains unclear. The aim of this study is to …

MicroRNAs as biomarkers for diagnosis, prognosis and theranostics in prostate cancer

G Bertoli, C Cava, I Castiglioni - International journal of molecular …, 2016 - mdpi.com
Prostate cancer (PC) includes several phenotypes, from indolent to highly aggressive
cancer. Actual diagnostic and prognostic tools have several limitations, and there is a need …

Development of a serum miRNA panel for detection of early stage non-small cell lung cancer

L Ying, L Du, R Zou, L Shi, N Zhang… - Proceedings of the …, 2020 - National Acad Sciences
Minimally invasive testing for early detection of lung cancer to improve patient survival is a
major unmet clinical need. This study aimed to develop and validate a serum multi …

MicroRNA‐375‐3p enhances chemosensitivity to 5‐fluorouracil by targeting thymidylate synthase in colorectal cancer

F Xu, ML Ye, YP Zhang, WJ Li, MT Li, HZ Wang… - Cancer …, 2020 - Wiley Online Library
Resistance to chemotherapy is a major challenge for the treatment of patients with colorectal
cancer (CRC). Previous studies have found that microRNAs (miRNAs) play key roles in drug …

MicroRNAs as regulators of insulin signaling: research updates and potential therapeutic perspectives in type 2 diabetes

L Nigi, GE Grieco, G Ventriglia, N Brusco… - International journal of …, 2018 - mdpi.com
The insulin signaling pathway is composed of a large number of molecules that positively or
negatively modulate insulin specific signal transduction following its binding to the cognate …