Molecular characteristics, immune evasion, and impact of SARS-CoV-2 variants

C Sun, C Xie, GL Bu, LY Zhong, MS Zeng - Signal Transduction and …, 2022 - nature.com
The persistent COVID-19 pandemic since 2020 has brought an enormous public health
burden to the global society and is accompanied by various evolution of the virus genome …

Development of new 2-(Benzothiazol-2-ylimino)-2, 3-dihydro-1H-imidazol-4-ol complexes as a robust catalysts for synthesis of thiazole 6-carbonitrile derivatives …

MAEAA Ali, O Elhady, A Abdou… - Journal of Molecular …, 2023 - Elsevier
Abstract Here, using Pd 2+, Fe 3+, and Ni 2+ ions, we established new imidazole
complexes. These complexes were described in the initial section to provide their chemical …

[HTML][HTML] Drug repurposing–A search for novel therapy for the treatment of diabetic neuropathy

A Paul, M Kumar, P Das, N Guha, M Rudrapal… - Biomedicine & …, 2022 - Elsevier
Diabetic neuropathy is a chronic complication to metabolic disorder, diabetes mellitus. Till
date, diagnosis and treatment of diabetic neuropathy remain elusive with challenges …

[HTML][HTML] Identification of bioactive molecules from Triphala (Ayurvedic herbal formulation) as potential inhibitors of SARS-CoV-2 main protease (Mpro) through …

M Rudrapal, I Celik, J Khan, MA Ansari… - Journal of King Saud …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus disease (SARS-CoV-2) induced coronavirus
disease 2019 (COVID-19) pandemic is the present worldwide health emergency. The global …

[HTML][HTML] Phytocompounds as potential inhibitors of SARS-CoV-2 Mpro and PLpro through computational studies

M Rudrapal, I Celik, S Chinnam, MA Ansari… - Saudi Journal of …, 2022 - Elsevier
The inhibition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main
protease (Mpro) and papain-like protease (PLpro) prevents viral multiplications; these viral …

Pt (IV) and Au (III) complexes with tridentate-benzothiazole based ligand: Synthesis, characterization, biological applications (antibacterial, antifungal, antioxidant …

HAK Kyhoiesh, KJ Al-Adilee - Inorganica Chimica Acta, 2023 - Elsevier
A novel tridentate azo dye ligand, 2-[2′-(6-methoxybenzothiazolyl) azo]-5-dimethylamino
benzoic acid (6-MBTADB) and its Pt (IV) and Au (III) metal complexes have been …

[HTML][HTML] Herbal concoction unveiled: a computational analysis of phytochemicals' pharmacokinetic and toxicological profiles using novel approach methodologies …

M Rai, AV Singh, N Paudel, A Kanase, E Falletta… - Current Research in …, 2023 - Elsevier
Herbal medications have an extensive history of use in treating various diseases, attributed
to their perceived efficacy and safety. Traditional medicine practitioners and contemporary …

Silybin phytosome attenuates cerebral ischemia‐reperfusion injury in rats by suppressing oxidative stress and reducing inflammatory response: In vivo and in silico …

PK Pasala, RK Uppara, M Rudrapal… - … of Biochemical and …, 2022 - Wiley Online Library
The present study was aimed to develop silybin phytosome (SIBP) and evaluate its
effectiveness against cerebral ischemia‐reperfusion (CIR) injury in rats. Initially, SIBP was …

Computational Investigations for Identification of Bioactive Molecules from Baccaurea ramiflora and Bergenia ciliata as Inhibitors of SARS-CoV-2 Mpro

JH Zothantluanga, M Abdalla, M Rudrapal… - Polycyclic Aromatic …, 2023 - Taylor & Francis
In this study, a hybrid compound library of 72 phytocompounds from two antiviral medicinal
plants (Baccaurea ramiflora and Bergenia ciliata) was computationally investigated for their …

Utilizing Andrographis paniculata leaves and roots by effective usage of the bioactive andrographolide and its nanodelivery: Investigation of antikindling and …

R Baru Venkata, DSNBK Prasanth, PK Pasala… - Frontiers in …, 2023 - frontiersin.org
To valorise the bioactive constituents abundant in leaves and other parts of medicinal plants
with the objective to minimize the plant-based wastes, this study was undertaken. The main …