Breast cancer is the leading cause of death in women aged 20–50 years, with some
geographical difference. The yearly incidence of the disease is increasing while the related …

The development of coronary artery disease, and specifically myocardial infarction, involves
hyperplasia of arterial smooth muscle, the development of fatty streaks, atheroma formation …

The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in
its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped …

Obese patients are at risk for the development of cardiovascular diseases, which can in part
be explained by disturbances in the haemostatic and fibrinolytic systems. Indeed, obese …

Background Variants of certain haemostatic genes (such as that encoding factor V Leiden)
are involved in the development of venous thrombosis, but studies of such variants in …

The development of thrombotic disorders in humans is one of the most common causes of
morbidity and mortality in the Western world. Thrombotic disease can be classified in broad …

Meta-analyses of population-based molecular association studies have become
increasingly common over the last 10 years, but little attention has been paid to …

Arterial thrombosis is a complex disorder that involves multiple genetic and environmental
factors interacting to produce the characteristic phenotype. In the past decades, investigators …

Osteonecrosis of the femoral head (ONFH) is a debilitating disease with major social and
economic impacts. It frequently affects relatively young adults and has a predilection for …

A number of prospective epidemiologic studies have now tested the hypothesis that plasma
measures of hemostatic factors measured in initially healthy subjects may predict the future …