Personalized medicine: motivation, challenges, and progress
LH Goetz, NJ Schork - Fertility and sterility, 2018 - Elsevier
There is a great deal of hype surrounding the concept of personalized medicine.
Personalized medicine is rooted in the belief that since individuals possess nuanced and …
Personalized medicine is rooted in the belief that since individuals possess nuanced and …
New frontiers in translational control of the cancer genome
ML Truitt, D Ruggero - Nature Reviews Cancer, 2016 - nature.com
The past several years have seen dramatic leaps in our understanding of how gene
expression is rewired at the translation level during tumorigenesis to support the …
expression is rewired at the translation level during tumorigenesis to support the …
Gynecologic cancers and non-coding RNAs: epigenetic regulators with emerging roles
ZS Razavi, V Tajiknia, S Majidi, M Ghandali… - Critical reviews in …, 2021 - Elsevier
Gynecologic cancers involve the female genital organs, such as the vulva, vagina, cervix,
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …
endometrium, ovaries, and fallopian tubes. The occurrence and frequency of gynecologic …
[HTML][HTML] CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence
Although the majority of low grade, early stage endometrial cancer patients will have good
survival outcomes with surgery alone, those patients who do recur tend to do poorly. Optimal …
survival outcomes with surgery alone, those patients who do recur tend to do poorly. Optimal …
Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating …
Extracellular vesicles (EVs) play a vital role in normal lung physiology to maintain
homeostasis in the airways via intercellular communication. EVs include exosomes and …
homeostasis in the airways via intercellular communication. EVs include exosomes and …
Non-coding RNAs targeting notch signaling pathway in cancer: From proliferation to cancer therapy resistance
M Hashemi, S Hasani, S Hajimazdarany… - International Journal of …, 2022 - Elsevier
Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless
advances in science has led to a decrease in the number of death cases caused by cancer …
advances in science has led to a decrease in the number of death cases caused by cancer …
[HTML][HTML] Dioscin protects against coronary heart disease by reducing oxidative stress and inflammation via Sirt1/Nrf2 and p38 MAPK pathways
B Yang, B Xu, H Zhao, YB Wang… - Molecular …, 2018 - spandidos-publications.com
Cardiovascular diseases are common diseases in Sweden as in most countries. In 2016,
25,700 persons suffered from coronary heart disease (CHD) and 25% of these died within …
25,700 persons suffered from coronary heart disease (CHD) and 25% of these died within …
[HTML][HTML] Cancer driver gene and non-coding RNA alterations as biomarkers of brain metastasis in lung cancer: a review of the literature
Brain metastasis (BM) is the most common event in patients with lung cancer. Despite
multimodal treatments and advances in systemic therapies, development of BM remains one …
multimodal treatments and advances in systemic therapies, development of BM remains one …
Box C/D snoRNA SNORD89 influences the occurrence and development of endometrial cancer through 2'-O-methylation modification of Bim
H Bao, X Chen, X Liu, W Wu, Q Li, J Xian, Y Zhao… - Cell Death …, 2022 - nature.com
The small nucleolar RNA (snoRNA) is a type of small non-coding RNA widely distributed in
the nucleoli of eukaryotic cells, promoting cancer development. The aim of this study was to …
the nucleoli of eukaryotic cells, promoting cancer development. The aim of this study was to …
Novel evidence for oncogenic piRNA‐823 as a promising prognostic biomarker and a potential therapeutic target in colorectal cancer
J Feng, M Yang, Q Wei, F Song, Y Zhang… - Journal of Cellular …, 2020 - Wiley Online Library
Abstract piRNA‐823 as a member of the piRNA family is reported to promote tumour cell
proliferation in multiple myeloma and hepatocellular cancer. However, few studies on the …
proliferation in multiple myeloma and hepatocellular cancer. However, few studies on the …