Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
[HTML][HTML] Cerebrovascular reactivity measurement using magnetic resonance imaging: a systematic review
E Sleight, MS Stringer, I Marshall, JM Wardlaw… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …
[HTML][HTML] Cerebrovascular reactivity mapping without gas challenges: a methodological guide
Cerebrovascular reactivity (CVR) is defined as the ability of vessels to alter their caliber in
response to vasoactive factors, by means of dilating or constricting, in order to increase or …
response to vasoactive factors, by means of dilating or constricting, in order to increase or …
Cerebral oxygen extraction fraction MRI: Techniques and applications
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …
[HTML][HTML] Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
Introduction Many consequences of cerebrovascular disease are identifiable by magnetic
resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of …
resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of …
Separating vascular and neuronal effects of age on fMRI BOLD signals
KA Tsvetanov, RNA Henson… - … Transactions of the …, 2021 - royalsocietypublishing.org
Accurate identification of brain function is necessary to understand the neurobiology of
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …
Direct assessment of extracerebral signal contamination on optical measurements of cerebral blood flow, oxygenation, and metabolism
Significance: Near-infrared spectroscopy (NIRS) combined with diffuse correlation
spectroscopy (DCS) provides a noninvasive approach for monitoring cerebral blood flow …
spectroscopy (DCS) provides a noninvasive approach for monitoring cerebral blood flow …
[HTML][HTML] A long duration of intraoperative hypotension is associated with postoperative delirium occurrence following thoracic and orthopedic surgery in elderly
W Duan, CM Zhou, JJ Yang, Y Zhang, ZP Li… - Journal of Clinical …, 2023 - Elsevier
Background Postoperative delirium (POD) is a common surgical complication associated
with increased morbidity and mortality in elderly. Although the underlying mechanisms …
with increased morbidity and mortality in elderly. Although the underlying mechanisms …
Cerebrovascular reactivity mapping using resting-state BOLD functional MRI in healthy adults and patients with Moyamoya disease
Background Cerebrovascular reserve, the potential capacity of brain tissue to receive more
blood flow when needed, is a desirable marker in evaluating ischemic risk. However, current …
blood flow when needed, is a desirable marker in evaluating ischemic risk. However, current …
[HTML][HTML] Vascular physiology drives functional brain networks
MG Bright, JR Whittaker, ID Driver, K Murphy - NeuroImage, 2020 - Elsevier
We present the first evidence for vascular regulation driving fMRI signals in specific
functional brain networks. Using concurrent neuronal and vascular stimuli, we collected 30 …
functional brain networks. Using concurrent neuronal and vascular stimuli, we collected 30 …