Histone phosphorylation: a chromatin modification involved in diverse nuclear events

D Rossetto, N Avvakumov, J Côté - Epigenetics, 2012 - Taylor & Francis
Histone posttranslational modifications are key components of diverse processes that
modulate chromatin structure. These marks function as signals during various chromatin …

[HTML][HTML] Chromatin modifications and their function

T Kouzarides - Cell, 2007 - cell.com
The surface of nucleosomes is studded with a multiplicity of modifications. At least eight
different classes have been characterized to date and many different sites have been …

[HTML][HTML] Epigenetic regulation of the histone-to-protamine transition during spermiogenesis

J Bao, MT Bedford - Reproduction (Cambridge, England), 2016 - ncbi.nlm.nih.gov
In mammals, male germ cells differentiate from haploid round spermatids to flagella-
containing motile sperm, in a process called spermiogenesis. This process is distinct from …

Sporulation in the Budding Yeast Saccharomyces cerevisiae

AM Neiman - Genetics, 2011 - academic.oup.com
In response to nitrogen starvation in the presence of a poor carbon source, diploid cells of
the yeast Saccharomyces cerevisiae undergo meiosis and package the haploid nuclei …

Essential role of histone replacement and modifications in male fertility

T Wang, H Gao, W Li, C Liu - Frontiers in genetics, 2019 - frontiersin.org
Spermiogenesis is a complex cellular differentiation process that the germ cells undergo a
distinct morphological change, and the protamines replace the core histones to facilitate …

Histone H4 lysine 16 acetylation regulates cellular lifespan

W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson… - Nature, 2009 - nature.com
Cells undergoing developmental processes are characterized by persistent non-genetic
alterations in chromatin, termed epigenetic changes, represented by distinct patterns of DNA …

Covalent modifications of histones during development and disease pathogenesis

SR Bhaumik, E Smith, A Shilatifard - Nature structural & molecular …, 2007 - nature.com
Covalent modifications of histones are central to the regulation of chromatin dynamics, and,
therefore, many biological processes involving chromatin, such as replication, repair …

Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

RH Cichewicz - Natural product reports, 2010 - pubs.rsc.org
Covering: up to the end of September 2009 The covalent modification of chromatin is an
important control mechanism used by fungi to modulate the transcription of genes involved …

Histone modifications and cancer

C Sawan, Z Herceg - Advances in genetics, 2010 - Elsevier
It is now widely recognized that epigenetic events are important mechanisms underlying
cancer development and progression. Epigenetic information in chromatin includes covalent …

A peek into the complex realm of histone phosphorylation

T Banerjee, D Chakravarti - Molecular and cellular biology, 2011 - Taylor & Francis
Although discovered long ago, posttranslational phosphorylation of histones has been in the
spotlight only recently. Information is accumulating almost daily on phosphorylation of …