There is increasing evidence in humans and laboratory animals for biologically based sex
differences in every phase of drug addiction: acute reinforcing effects, transition from …

The hippocampus has been implicated in modulating anxiety. It interacts with a variety of
brain regions, both cortical and subcortical areas regulating emotion and stress responses …

In recent years, striking new evidence has demonstrated non-genetic inheritance of
acquired traits associated with parental environmental exposures. In particular, this …

Tau hyperphosphorylation in hippocampal neurons has an important pathogenetic role in
the development of diabetic cognitive dysfunction. N6-methyladenosine (m6A) methylation …

Addictions are highly heritable disorders, with heritability estimates ranging from 39% to
72%. Multiple studies suggest a link between paternal drug abuse and addiction in their …

Early-life stress is a potent risk factor for development of psychiatric conditions such as
depression. The underlying mechanisms remain poorly understood. Here, we used the early …

Susceptibility to psychiatric disorders seems to be influenced by environmental disturbances
throughout all stages of life. Epigenetics is described as a key “bridge” between gene and …

Prescription opiate use and abuse has increased dramatically over the past two decades,
including increased use in adolescent populations. Recently, it has been proposed that use …

Background Although in all sexually reproducing organisms an individual has a mother and
a father, non-genetic inheritance has been predominantly studied in mothers. Paternal …

Previous studies suggest that serotonin (5-HT) might interact with brain-derived neurotrophic
factor (BDNF) during the stress response. However, the relationship between 5-HT and …