The cytokine mediated molecular pathophysiology of psoriasis and its clinical implications

R Singh, S Koppu, PO Perche, SR Feldman - International journal of …, 2021 - mdpi.com
Psoriasis is the result of uncontrolled keratinocyte proliferation, and its pathogenesis
involves the dysregulation of the immune system. The interplay among cytokines released …

The efficacy and safety of tofacitinib, peficitinib, solcitinib, baricitinib, abrocitinib and deucravacitinib in plaque psoriasis–A network meta‐analysis

L Zhang, L Guo, L Wang, X Jiang - Journal of the European …, 2022 - Wiley Online Library
Janus kinase (JAK) inhibitors are novel treatment approaches for psoriasis. However, there
is no direct comparison of JAK inhibitors in plaque psoriasis. In order to compare the efficacy …

[HTML][HTML] Academic Textbook: The Role of Melatonin in Pathogenesis and Treatment of Autoimmune Diseases

SOH Tabatabaei, R Moazamiyanfar, AM Fard… - Kindle, 2022 - preferpub.org
An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

Curcumin-based nanomedicines in the treatment of inflammatory and immunomodulated diseases: An evidence-based comprehensive review

LF Laurindo, GM de Carvalho, B de Oliveira Zanuso… - Pharmaceutics, 2023 - mdpi.com
Curcumin (CUR) is a polyphenol extracted from the rhizome of Curcuma longa that
possesses potent anti-inflammatory and antioxidant potential. Despite CUR's numerous …

Current developments and perspectives in psoriasis

MP Schön, D Wilsmann‐Theis - JDDG: Journal Der Deutschen …, 2023 - Wiley Online Library
The study of psoriasis has yielded fundamental new insights into immunologic regulation
and innovative therapies in a way that few other diseases have. In this review, we …

Immune cells in the epithelial immune microenvironment of psoriasis: emerging therapeutic targets

L Li, J Lu, J Liu, J Wu, X Zhang, Y Meng, X Wu… - Frontiers in …, 2024 - frontiersin.org
Psoriasis is a chronic autoimmune inflammatory disease characterized by erroneous
metabolism of keratinocytes. The development of psoriasis is closely related to abnormal …

Hyaluronic acid engineered gallic acid embedded chitosan nanoparticle as an effective delivery system for treatment of psoriasis

A Sheikh, SA Hazari, N Molugulu, SA Alshehri… - Environmental …, 2023 - Elsevier
Psoriasis is a deleterious auto-immune disorder which seriously harms the patients physical
and mental health. CD44 are found to be over-expressed on psoriatic lesions which are …

Etiopathogenesis of Psoriasis: Integration of Proposed Theories

BF Hernandez-Nicols, JJ Robledo-Pulido… - Immunological …, 2024 - Taylor & Francis
Psoriasis is a chronic inflammatory disease characterized by squamous and erythematous
plaques on the skin and the involvement of the immune system. Global prevalence for …

Topically applied pH-responsive nanogels for alkyl radical-based therapy against psoriasiform hyperplasia

GR Nirmal, CC Liao, ZC Lin, A Alshetaili, E Hwang… - Drug Delivery, 2023 - Taylor & Francis
Phototherapy is a conventional antipsoriatic approach based on oxygen-relevant generation
of oxidative stress to inhibit keratinocyte hyperproliferation. However, this therapy can be …

Analysis of PPARγ Signaling Activity in Psoriasis

V Sobolev, A Nesterova, A Soboleva… - International Journal of …, 2021 - mdpi.com
In our previous work, we built the model of PPARγ dependent pathways involved in the
development of the psoriatic lesions. Peroxisome proliferator-activated receptor gamma …