[HTML][HTML] Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease

Q Yan, S Liu, Y Sun, C Chen, S Yang, M Lin… - Journal of Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality
rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis …

Recent advances in electrochemical nanobiosensors for cardiac biomarkers

M Negahdary, A Sharma, TD Anthopoulos… - TrAC Trends in Analytical …, 2023 - Elsevier
The WHO reports heart diseases, especially MI, are the leading cause of death. During a
heart attack and damage to myocardial cells, cardiac biomarkers are released into the …

[HTML][HTML] Protective mechanisms of 10-gingerol against myocardial ischemia may involve activation of JAK2/STAT3 pathway and regulation of Ca2+ homeostasis

X Han, J Qi, Y Yang, B Zheng, M Liu, Y Liu, L Li… - Biomedicine & …, 2022 - Elsevier
Gingerol (10-Gin), an active ingredient extracted from ginger, has been reported to have
beneficial effects on the cardiovascular system. However, its protective effects on myocardial …

[HTML][HTML] Cardioprotective effects of Callicarpa tomentosa leaf extract in Wistar albino rats against isoproterenol-induced myocardial necrosis: Phytochemical analysis …

N Noushida, RP Nayak, R Sultana, TR Salian… - Journal of King Saud …, 2024 - Elsevier
Background Globally, cardiovascular disease (CVD) remains the foremost cause of
mortality. Conventional medications are associated with several complications …

[HTML][HTML] 6-Gingerol, an ingredient of Zingiber officinale, abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing oxidative stress and inflammation

A Hosseini, MS Alavi, MGN Toos… - Journal of Agriculture …, 2024 - Elsevier
Background Sepsis-induced cardiac dysfunction is the main reason for the high mortality
rate in patients with sepsis. For centuries, ginger has been used as a spice and a natural …

PEG-modified nano liposomes co-deliver Apigenin and RAGE-siRNA to protect myocardial ischemia injury

C Liu, X Zhang, H Yang, M Zhao, Y Liu, R Zhao… - International Journal of …, 2024 - Elsevier
Ischemic heart disease (IHD) is a cardiac disorder in which myocardial damage occurs as a
result of myocardial ischemia and hypoxia. Evidence suggests that oxidative stress and …

[HTML][HTML] TMT-based proteomics reveals methylprotodioscin alleviates oxidative stress and inflammation via COX6C in myocardial infraction

Z Xu, T Song, X Yang, L Cong, L Yin, Y Xu… - Biomedicine & …, 2024 - Elsevier
The effect of methylprotodioscin (MPD), a steroidal saponin obtained from medicinal plants,
on myocardial infarction (MI) remains elusive. In this study, HL-1 and AC16 cells were …

Phytoconstituents with cardioprotective properties: A pharmacological overview on their efficacy against myocardial infarction

A Ullah, NM Mostafa, SA Halim… - Phytotherapy …, 2024 - Wiley Online Library
Myocardial infarction (MI) is considered one of the most common cardiac diseases and
major cause of death worldwide. The prevalence of MI and MI‐associated mortality have …

Effect of folic acid on isoprenaline-induced myocardial injury in rats

T Sobot, Z Bajic, R Skrbic, S Uletilovic… - Physiology …, 2024 - akjournals.com
Background Isoprenaline (ISO), a synthetic catecholamine and a β-adrenoceptor agonist, is
widely used to develop an experimental model of myocardial injury (MI) in rats. The leading …

[HTML][HTML] Cardioprotective Effect of Rheum turkestanicum Against Doxorubicin-Induced Toxicity in Rats

A Hosseini, MK Safari, A Rajabian… - Frontiers in …, 2022 - frontiersin.org
Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability
and use. The mechanism of toxicity is due to free radical production and cardiomyocytes …