Preanalytical variables affecting the integrity of human biospecimens in biobanking

C Ellervik, J Vaught - Clinical chemistry, 2015 - academic.oup.com
BACKGROUND Most errors in a clinical chemistry laboratory are due to preanalytical errors.
Preanalytical variability of biospecimens can have significant effects on downstream …

Guidelines for the preanalytical conditions for analyzing circulating cell-free DNA

R Meddeb, E Pisareva, AR Thierry - Clinical chemistry, 2019 - academic.oup.com
Circulating cell-free DNA (cfDNA) isolated from blood has been identified as a potential
biomarker in numerous fields, and has been the object of intensive research over the past …

[HTML][HTML] Prediagnostic selenium status, selenoprotein gene variants and association with breast cancer risk in a European cohort study

DJ Hughes, L Schomburg, M Jenab, C Biessy… - Free Radical Biology …, 2023 - Elsevier
Selenium (Se) may help prevent breast cancer (BC) development. Owing to limited
observational evidence, we investigated whether prediagnostic Se status and/or variants in …

Evaluating minimally invasive sample collection methods for telomere length measurement

EA Goldman, GN Eick, D Compton… - American Journal of …, 2018 - Wiley Online Library
Objectives Telomere length (TL) is a biomarker of aging and age‐related decline. Although
venous blood is considered the “gold standard” for TL measurement, its collection is often …

[HTML][HTML] Saliva DNA quality and genotyping efficiency in a predominantly elderly population

HV Gudiseva, M Hansen, L Gutierrez, DW Collins… - BMC medical …, 2016 - Springer
Background The question of whether DNA obtained from saliva is an acceptable alternative
to DNA from blood is a topic of considerable interest for large genetics studies. We …

[HTML][HTML] Association of selenoprotein and selenium pathway genotypes with risk of colorectal cancer and interaction with selenium status

V Fedirko, M Jenab, C Méplan, JS Jones, W Zhu… - Nutrients, 2019 - mdpi.com
Selenoprotein genetic variations and suboptimal selenium (Se) levels may contribute to the
risk of colorectal cancer (CRC) development. We examined the association between CRC …

DNA microarray for forensic intelligence purposes: High-density SNP profiles obtained directly from casework-like samples with and without a DNA purification step

GO Urtiaga, WB Domingues, ER Komninou… - Forensic Science …, 2022 - Elsevier
SNP analyses from a forensic intelligence perspective have proven to be an important tool to
restrict the number of suspected offenders and find missing persons. DNA microarray assays …

A practical guide to epidemiological practice and standards in the identification and validation of diagnostic markers using a bladder cancer example

T Behrens, N Bonberg, S Casjens, B Pesch… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Technical advances to analyze biological markers have generated a plethora of promising
new marker candidates for early detection of cancer. However, in subsequent analyses only …

DNA from nails for genetic analyses in large-scale epidemiologic studies

JGF Hogervorst, RWL Godschalk… - … Biomarkers & Prevention, 2014 - AACR
Background: Nails contain genomic DNA that can be used for genetic analyses, which is
attractive for large epidemiologic studies that have collected or are planning to collect nail …

Automation of DNA and miRNA co‐extraction for miRNA‐based identification of human body fluids and tissues

G Kulstein, R Marienfeld, E Miltner… - Electrophoresis, 2016 - Wiley Online Library
In the last years, microRNA (miRNA) analysis came into focus in the field of forensic
genetics. Yet, no standardized and recommendable protocols for co‐isolation of miRNA and …