Suicidal behavior in older adults (65 years old and over) is a major public health issue in
many countries. Suicide rates increase during the life course and are as high as …

Background Anhedonia is considered a suicide risk factor in patients with major affective
disorders. Here, we wanted to quantify the association between anhedonia and current …

Objective To confirm the rapid onset anti-suicidal benefits of ketamine in the short term and
at six weeks, overall and according to diagnostic group. Design Prospective, double blind …

Abstract Purpose of Review The definition of psychological pain is complex. It is a lasting
unpleasant and unsustainable feeling characterized by a perception of inability or deficiency …

We recently reported that naltrexone blocks antidepressant effects of ketamine in humans,
indicating that antidepressant effects of ketamine require opioid receptor activation …

Suicide is a major public health problem, and suicide rates are still on the rise. Current
strategies for identifying individuals at risk for suicide, such as the use of a patient's self …

The number of psychiatric patients requesting Euthanasia or Assisted Suicide (EAS)
continues to increase. The aims of this systematic review were to: 1) describe the available …

Background: More than 2% of the general population experience suicidal ideas each year
and a large number of them will attempt suicide. Evidence-based therapeutic options to …

Abstract Background and Aim The Suicide Crisis Syndrome (SCS) is an evidence-based pre-
suicidal cognitive and affective state predictive of short-term suicide risk. The most recent …

Suicidal behaviour is a multifaceted phenomenon that concerns all human populations. It
has been suggested that a complex interaction between the individual genetic profile and …