Pathogenesis of epileptic seizures and epilepsy after stroke

H Yang, G Rajah, A Guo, Y Wang, Q Wang - Neurological research, 2018 - Taylor & Francis
Stroke is an important cause of seizures and epilepsy in adults, particularly among the
elderly. The incidence of stroke increases yearly as life expectancy increases and the …

Update on statin treatment in patients with neuropsychiatric disorders

R Avan, A Sahebnasagh, J Hashemi, M Monajati… - Life, 2021 - mdpi.com
Statins are widely accepted as first-choice agents for the prevention of lipid-related
cardiovascular diseases. These drugs have both anti-inflammatory and anti-oxidant …

Anticonvulsant activity of resveratrol-loaded liposomes in vivo

MS Ethemoglu, FB Seker, H Akkaya, E Kilic, I Aslan… - Neuroscience, 2017 - Elsevier
Abstract Resveratrol (3, 5, 4′-stilbenetriol), a natural polyphenol produced by various
plants, has attracted attention over the past decade because of its multiple beneficial …

Biocatalyzed synthesis of statins: A sustainable strategy for the preparation of valuable drugs

P Hoyos, V Pace, AR Alcántara - Catalysts, 2019 - mdpi.com
Statins, inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, are the
largest selling class of drugs prescribed for the pharmacological treatment of …

[HTML][HTML] Impact of drug treatment and drug interactions in post-stroke epilepsy

L Zhao, J Li, R Kälviäinen, J Jolkkonen… - Pharmacology & …, 2022 - Elsevier
Stroke is a huge burden on our society and this is expected to grow in the future due to the
aging population and the associated co-morbidities. The improvement of acute stroke care …

Repurposing of cholesterol-lowering agents in status epilepticus: A neuroprotective effect of simvastatin

A Hanin, D Roussel, S Lecas, P Baudin, V Navarro - Epilepsy & Behavior, 2023 - Elsevier
The increase of cholesterol synthesis after a status epilepticus may lead to excitotoxic
processes, neuronal loss and favor the appearance of spontaneous epileptic seizures …

Statin treatment can reduce incidence of early seizure in acute ischemic stroke: A propensity score analysis

S Matsubara, T Tanaka, S Tomari, K Fukuma… - Scientific reports, 2020 - nature.com
A previous study showed early statin administration in patients with acute ischemic stroke
(AIS) was associated with a lower risk of early-onset seizure (ES), which is a high risk of …

Statin on post-stroke epilepsy: a systematic review and meta-analysis

J Fang, M Tuo, K Ouyang, Y Xu - Journal of Clinical Neuroscience, 2021 - Elsevier
Introduction Recent research has shown that statins can reduce the incidence of epilepsy
after stroke, especially ischemic stroke, but the results are inconsistent. In view of current …

[HTML][HTML] Efficacy of Statin therapy in post-stroke seizure prophylaxis: Clues from an observational study of routine secondary prevention treatment

Y Li, B Zhang, L Zhang, D Xie, Y Li - Seizure, 2019 - Elsevier
Purpose To confirm that statin use can reduce the risk of post-stroke seizures (PSS), and to
further investigate the association between the details of specific statin therapy, including the …

Dichlorvos poisoning caused chicken cerebrum tissue damage and related apoptosis-related gene changes

Y Gu, G Li, C Huang, P Liu, G Hu, C Wu, Z Xu… - Science of the Total …, 2021 - Elsevier
Dichlorvos (DDVP) is an organophosphorus compound with insecticidal effects.
Organophosphorus pesticides can easily enter humans or animals through various …