The endocannabinoid system (ECS), comprising two G protein-coupled receptors (the
cannabinoid receptors 1 and 2 [CB1 and CB2] for marijuana's psychoactive principle∆ 9 …

Extensive evidence indicates that endocannabinoids modulate cognitive processes in
animal models and human subjects. However, the results of endocannabinoid system …

The endocannabinoid system via cannabinoid (CB: CB1 and CB2) receptors and their
endogenous ligands is directly and indirectly involved in many physiological functions …

Preclinical and clinical data fully support the involvement of the endocannabinoid system in
the etiopathogenesis of several mental diseases. In this review we will briefly summarize the …

Exposure to stressful situations is one of the risk factors for the precipitation of several
psychiatric disorders, including Major Depressive Disorder, Posttraumatic Stress Disorder …

The endocannabinoid (eCB) system is a lipid-based neurotransmitter complex that plays
crucial roles in the neural control of learning and memory. The current model of eCB …

Communication between neuronal and glial cells is thought to be very important for many
brain functions. Acting via release of gliotransmitters, astrocytes can modulate synaptic …

Abstract The endocannabinoid 2-arachidonoyl-sn-glycerol (2-AG), a key modulator of
synaptic transmission in mammalian brain, is produced in dendritic spines and then crosses …

The cannabinoid receptor type 1 (CB1) is abundantly expressed in the central nervous
system where it negatively controls the release of several neurotransmitters. CB1 activity …

It is well known that physical exercise has positive effects on cognitive functions and
hippocampal plasticity. However, the underlying mechanisms have remained to be further …