Endocannabinoid system and mood disorders: priming a target for new therapies
The endocannabinoid system (ECS), comprising two G protein-coupled receptors (the
cannabinoid receptors 1 and 2 [CB1 and CB2] for marijuana's psychoactive principle∆ 9 …
cannabinoid receptors 1 and 2 [CB1 and CB2] for marijuana's psychoactive principle∆ 9 …
The endocannabinoid system: an emotional buffer in the modulation of memory function
M Morena, P Campolongo - Neurobiology of Learning and Memory, 2014 - Elsevier
Extensive evidence indicates that endocannabinoids modulate cognitive processes in
animal models and human subjects. However, the results of endocannabinoid system …
animal models and human subjects. However, the results of endocannabinoid system …
[HTML][HTML] Endocannabinoid system: the direct and indirect involvement in the memory and learning processes—a short review
M Kruk-Slomka, A Dzik, B Budzynska, G Biala - Molecular neurobiology, 2017 - Springer
The endocannabinoid system via cannabinoid (CB: CB1 and CB2) receptors and their
endogenous ligands is directly and indirectly involved in many physiological functions …
endogenous ligands is directly and indirectly involved in many physiological functions …
Endocannabinoids and mental disorders
TI Rubino, E Zamberletti, D Parolaro - Endocannabinoids, 2015 - Springer
Preclinical and clinical data fully support the involvement of the endocannabinoid system in
the etiopathogenesis of several mental diseases. In this review we will briefly summarize the …
the etiopathogenesis of several mental diseases. In this review we will briefly summarize the …
[HTML][HTML] Cannabinoid modulation of the stressed hippocampus
FF Scarante, C Vila-Verde, VL Detoni… - Frontiers in molecular …, 2017 - frontiersin.org
Exposure to stressful situations is one of the risk factors for the precipitation of several
psychiatric disorders, including Major Depressive Disorder, Posttraumatic Stress Disorder …
psychiatric disorders, including Major Depressive Disorder, Posttraumatic Stress Disorder …
[HTML][HTML] Lights on endocannabinoid-mediated synaptic potentiation
The endocannabinoid (eCB) system is a lipid-based neurotransmitter complex that plays
crucial roles in the neural control of learning and memory. The current model of eCB …
crucial roles in the neural control of learning and memory. The current model of eCB …
Cannabinoid receptors contribute to astroglial Ca2+-signalling and control of synaptic plasticity in the neocortex
S Rasooli-Nejad, O Palygin… - … Transactions of the …, 2014 - royalsocietypublishing.org
Communication between neuronal and glial cells is thought to be very important for many
brain functions. Acting via release of gliotransmitters, astrocytes can modulate synaptic …
brain functions. Acting via release of gliotransmitters, astrocytes can modulate synaptic …
A primary cortical input to hippocampus expresses a pathway-specific and endocannabinoid-dependent form of long-term potentiation
Abstract The endocannabinoid 2-arachidonoyl-sn-glycerol (2-AG), a key modulator of
synaptic transmission in mammalian brain, is produced in dendritic spines and then crosses …
synaptic transmission in mammalian brain, is produced in dendritic spines and then crosses …
Cannabinoid CB1 receptor deficiency increases contextual fear memory under highly aversive conditions and long-term potentiation in vivo
W Jacob, R Marsch, G Marsicano, B Lutz… - Neurobiology of learning …, 2012 - Elsevier
The cannabinoid receptor type 1 (CB1) is abundantly expressed in the central nervous
system where it negatively controls the release of several neurotransmitters. CB1 activity …
system where it negatively controls the release of several neurotransmitters. CB1 activity …
A role for the endocannabinoid system in exercise‐induced spatial memory enhancement in mice
TH Ferreira‐Vieira, CP Bastos, GS Pereira… - …, 2014 - Wiley Online Library
It is well known that physical exercise has positive effects on cognitive functions and
hippocampal plasticity. However, the underlying mechanisms have remained to be further …
hippocampal plasticity. However, the underlying mechanisms have remained to be further …