With the large-scale use of antibiotics, antibiotic resistant bacteria (ARB) continue to rise,
and antibiotic resistance genes (ARGs) are regarded as emerging environmental pollutants …

Understanding the mechanisms leading to the rise and dissemination of antimicrobial
resistance (AMR) is crucially important for the preservation of power of antimicrobials and …

The propagation of antimicrobial resistance (AMR) is constantly paralyzing our healthcare
systems. In addition to the pressure of antibiotic selection, the roles of non-antibiotic …

The widespread dissemination of antibiotic resistance genes (ARGs) is a serious problem
and constitutes a threat for public health. Plasmid-mediated conjugative transfer of ARGs is …

In recent years, the plasmid-mediated transmission of the tigecycline resistance gene tet (X)
in Escherichia coli has received considerable attention. However, studies on the global …

The recently emerged plasmid-mediated tigecycline resistance gene tet (X4) has mainly
been detected in Escherichia coli but never in Klebsiella pneumoniae. Herein, we identified …

The emergence of extensive drug-resistant (XDR) Salmonella in livestock animals
especially in poultry represents a serious public health and therapeutic challenge. Despite …

The recent emergence of mobile-tigecycline resistance tet (X) genes in human and animals
in China seriously threats the clinical utility of tigecycline. Here we focused on the isolation …

The emergence of plasmid-mediated tigecycline resistance genes has attracted a great deal
of attention globally. Currently, no comprehensive in-depth genomic epidemiology study of …

The emergence of novel antimicrobial resistance genes conferring resistance to last-resort
antimicrobials poses a serious challenge to global public health security. Recently, one …