Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs
KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
Naturally-sourced antibacterial polymeric nanomaterials with special reference to modified polymer variants
M Rofeal, F Abdelmalek, A Steinbüchel - International Journal of …, 2022 - mdpi.com
Despite the recent advancements in treating bacterial infections, antibiotic resistance (AR) is
still an emerging issue. However, polymeric nanocarriers have offered unconventional …
still an emerging issue. However, polymeric nanocarriers have offered unconventional …
Fabrication of pH-responsive hydrogels of perindopril erbumine using black seed extract and β-cyclodextrin co-polymerized with methacrylic acid and methylene …
F Noor, A Mahmood, N Zafar, RM Sarfraz… - Journal of Drug Delivery …, 2023 - Elsevier
This study aimed to create an intelligent pH-responsive system for the controlled release of
perindopril erbumine using natural black seed extract and β-cyclodextrin as polymers …
perindopril erbumine using natural black seed extract and β-cyclodextrin as polymers …
Preparation and study of polyvinyl alcohol gel structures with acrylamide and 2-acrylamido-2-methyl-1-propanesulfonic acid for application in saline oil reservoirs for …
S Dong, L Li, Y Wu, X Huang… - ACS Applied Materials & …, 2023 - ACS Publications
Polymer gels can be effectively applied to plug fractured reservoirs and carbonate cave
strata. Herein, polyvinyl alcohol (PVA), acrylamide, and 2-acrylamido-2-methyl-1 …
strata. Herein, polyvinyl alcohol (PVA), acrylamide, and 2-acrylamido-2-methyl-1 …
Synthesis and characterization of carboxymethyl chitosan nanosponges with cyclodextrin blends for drug solubility improvement
SSB Rizvi, N Akhtar, MU Minhas, A Mahmood… - Gels, 2022 - mdpi.com
This study aimed to enhance the solubility and release characteristics of docetaxel by
synthesizing highly porous and stimuli responsive nanosponges, a nano-version of …
synthesizing highly porous and stimuli responsive nanosponges, a nano-version of …
Voriconazole cyclodextrin based polymeric nanobeads for enhanced solubility and activity: in vitro/in vivo and molecular simulation approach
Hydroxypropyl β-cyclodextrin (HPβCD) based polymeric nanobeads containing
voriconazole (VRC) were fabricated by free radical polymerization using N, N′-methylene …
voriconazole (VRC) were fabricated by free radical polymerization using N, N′-methylene …
Evaluation of suitable polymeric matrix/carriers during loading of poorly water soluble drugs onto mesoporous silica: Physical stability and in vitro supersaturation
A Kapourani, K Katopodis, V Valkanioti… - Polymers, 2024 - mdpi.com
The application of mesoporous carriers in formulations of amorphous solid dispersions
(ASDs) has been suggested to enhance the stability of amorphous drugs. However …
(ASDs) has been suggested to enhance the stability of amorphous drugs. However …
Designing of pH-sensitive hydrogels for colon targeted drug delivery; characterization and in vitro evaluation
M Suhail, YF Shao, QL Vu, PC Wu - Gels, 2022 - mdpi.com
In the current research work, pH-sensitive hydrogels were prepared via a free radical
polymerization technique for the targeted delivery of 5-aminosalicylic acid to the colon …
polymerization technique for the targeted delivery of 5-aminosalicylic acid to the colon …
[Retracted] Polyvinylpyrrolidone K‐30‐Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement
MU Minhas, KU Khan, M Sarfraz… - BioMed Research …, 2022 - Wiley Online Library
Poor solubility is a global issue of copious pharmaceutical industries as large number of
drugs in development stage as well as already marketed products are poorly soluble which …
drugs in development stage as well as already marketed products are poorly soluble which …
β-cyclodextrin-based nanosponges inclusion compounds associated with gold nanorods for potential NIR-II drug delivery
S Salazar Sandoval, E Cortés-Adasme… - Pharmaceutics, 2022 - mdpi.com
This article describes the synthesis and characterization of two nanocarriers consisting of β-
cyclodextrin-based nanosponges (NSs) inclusion compounds (ICs) and gold nanorods …
cyclodextrin-based nanosponges (NSs) inclusion compounds (ICs) and gold nanorods …