A framework for fibrolamellar carcinoma research and clinical trials
Fibrolamellar carcinoma (FLC), a rare, lethal hepatic cancer, occurs primarily in adolescents
and young adults. Unlike hepatocellular carcinoma, FLC has no known association with …
and young adults. Unlike hepatocellular carcinoma, FLC has no known association with …
Fibrolamellar carcinoma: An entity all its own
AF O'Neill, AJ Church, AR Perez-Atayde… - Current Problems in …, 2021 - Elsevier
Fibrolamellar carcinoma (FLC) is a rare malignant entity arising from the liver and primarily
affecting patients in late adolescence and young adulthood. FLC tumors are characterized …
affecting patients in late adolescence and young adulthood. FLC tumors are characterized …
New insights in the control of fat homeostasis: the role of neurotensin
I Barchetta, MG Baroni, O Melander… - International Journal of …, 2022 - mdpi.com
Neurotensin (NT) is a small peptide with pleiotropic functions, exerting its primary actions by
controlling food intake and energy balance. The first evidence of an involvement of NT in …
controlling food intake and energy balance. The first evidence of an involvement of NT in …
The cAMP-signaling cancers: Clinically-divergent disorders with a common central pathway
GB Bolger - Frontiers in Endocrinology, 2022 - frontiersin.org
The cAMP-signaling cancers, which are defined by functionally-significant somatic mutations
in one or more elements of the cAMP signaling pathway, have an unexpectedly wide range …
in one or more elements of the cAMP signaling pathway, have an unexpectedly wide range …
The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review
Background Neurotensin, originally isolated in 1973 has both endocrine and
neuromodulator activity and acts through its three main receptors. Their role in promoting …
neuromodulator activity and acts through its three main receptors. Their role in promoting …
Higher circulating levels of proneurotensin are associated with increased risk of incident NAFLD
F De Vito, V Cassano, E Mancuso… - Journal of Internal …, 2023 - Wiley Online Library
Background Neurotensin (NT), an intestinal peptide able to promote fat absorption, is
implicated in the pathogenesis of obesity. Increased levels of proneurotensin (pro‐NT), a …
implicated in the pathogenesis of obesity. Increased levels of proneurotensin (pro‐NT), a …
DnaJ-PKAc fusion induces liver inflammation in a zebrafish model of fibrolamellar carcinoma
S De Oliveira, RA Houseright… - Disease models & …, 2020 - journals.biologists.com
Fibrolamellar carcinoma (FLC) is a rare liver cancer that affects adolescents and young
adults. Genomic analysis of FLC has revealed a 400 kb deletion in chromosome 19 that …
adults. Genomic analysis of FLC has revealed a 400 kb deletion in chromosome 19 that …
Expression of neurotensin receptor-1 (NTS1) in primary breast tumors, cellular distribution, and association with clinical and biological factors
C Morgat, V Brouste, A Chastel, V Vélasco… - Breast Cancer Research …, 2021 - Springer
Abstract Purpose Neurotensin receptor-1 (NTS 1) is increasingly recognized as a potential
target in diverse tumors including breast cancer, but factors associated with NTS 1 …
target in diverse tumors including breast cancer, but factors associated with NTS 1 …