A comprehensive review of emerging trends and innovative therapies in epilepsy management

S Ghosh, JK Sinha, S Ghosh, H Sharma, R Bhaskar… - Brain Sciences, 2023 - mdpi.com
Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …

Insights into epileptogenesis from post-traumatic epilepsy

M Pease, K Gupta, SL Moshé, DJ Correa… - Nature Reviews …, 2024 - nature.com
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

Matching assistive technology, telerehabilitation, and virtual reality to promote cognitive rehabilitation and communication skills in neurological populations: a …

F Stasolla, A Lopez, K Akbar, LA Vinci, M Cusano - Technologies, 2023 - mdpi.com
Neurological populations (NP) commonly experience several impairments. Beside motor
and sensorial delays, communication and intellectual disabilities are included. The COVID …

Transcriptomic alterations in cortical astrocytes following the development of post-traumatic epilepsy

J Leonard, X Wei, J Browning… - Scientific Reports, 2024 - nature.com
Post-traumatic epilepsy (PTE) stands as one of the numerous debilitating consequences that
follow traumatic brain injury (TBI). Despite its impact on many individuals, the current …

The integration of assistive technology and virtual reality for assessment and recovery of post-coma patients with disorders of consciousness: a new hypothesis

F Stasolla, LA Vinci, M Cusano - Frontiers in Psychology, 2022 - frontiersin.org
Multiple disabilities due to an outcome of coma combined with severe to profound disorders
of consciousness may pose serious challenges to daily medical centers and rehabilitative …

[HTML][HTML] Exploring the neuroinflammatory pathway in epilepsy and cognitive impairment: Role of HMGB1 and translational challenges

IW Ngadimon, EA Seth, MF Shaikh - Frontiers in Bioscience …, 2024 - imrpress.com
Neuroinflammation has emerged as a shared molecular mechanism in epilepsy and
cognitive impairment, offering new insights into the complex interplay between immune …

Incidence and predictors of posttraumatic epilepsy and cognitive impairment in patients with traumatic brain injury: A retrospective cohort study in Malaysia

IW Ngadimon, D Mohan, MF Shaikh, CS Khoo… - …, 2024 - Wiley Online Library
Objective Posttraumatic epilepsy (PTE) significantly impacts morbidity and mortality, yet local
PTE data remain scarce. In addition, there is a lack of evidence on cognitive comorbidity in …

Pre-existing Toxoplasma gondii infection increases susceptibility to pentylenetetrazol-induced seizures independent of traumatic brain injury in mice

TL Baker, AD Uboldi, CJ Tonkin, DK Wright… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction Post-traumatic epilepsy (PTE) is a debilitating chronic outcome of traumatic
brain injury (TBI), and neuroinflammation is implicated in increased seizure susceptibility …

Complications and Long-Term Outcomes of Shunted Post-Traumatic Hydrocephalus: A Single-Center Series

EA Grin, A Eremiev, A Palla, D de Souza… - Neurotrauma …, 2024 - liebertpub.com
Post-traumatic hydrocephalus (PTH) is a particularly challenging complication of traumatic
brain injury (TBI). The primary treatment for PTH is placement of a ventricular shunt …

[HTML][HTML] Post-Traumatic Epilepsy: Observations from an Urban Level 1 Trauma Center

D Kotas, H Zhao, J Turella, WS Kasoff - Neurology International, 2024 - mdpi.com
There are approximately 2.5 million cases of traumatic brain injury (TBI) in the US each year.
Post-traumatic epilepsy (PTE), a sequela of TBI, has been shown to occur in approximately …