Roles of nucleus accumbens core and shell in incentive-cue responding and behavioral inhibition

F Ambroggi, A Ghazizadeh, SM Nicola… - Journal of …, 2011 - Soc Neuroscience
The nucleus accumbens (NAc) is involved in many reward-related behaviors. The NAc has
two major components, the core and the shell. These two areas have different inputs and …

[HTML][HTML] Ventral pallidum neurons encode incentive value and promote cue-elicited instrumental actions

JM Richard, F Ambroggi, PH Janak, HL Fields - Neuron, 2016 - cell.com
The ventral pallidum (VP) is posited to contribute to reward seeking by conveying upstream
signals from the nucleus accumbens (NAc). Yet, very little is known about how VP neuron …

Prefrontal cortex mediates extinction of responding by two distinct neural mechanisms in accumbens shell

A Ghazizadeh, F Ambroggi, N Odean… - Journal of …, 2012 - Soc Neuroscience
Suppression of ill-timed or competing actions optimizes goal-directed behaviors. Diminished
inhibitory control over such actions is a central feature of such disorders as impulsivity …

[HTML][HTML] Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure

JM Richard, N Stout, D Acs, PH Janak - Elife, 2018 - elifesciences.org
Despite its being historically conceptualized as a motor expression site, emerging evidence
suggests the ventral pallidum (VP) plays a more active role in integrating information to …

Temporal–prefrontal cortical network for discrimination of valuable objects in long-term memory

A Ghazizadeh, W Griggs… - Proceedings of the …, 2018 - National Acad Sciences
Remembering and discriminating objects based on their previously learned values are
essential for goal-directed behaviors. While the cerebral cortex is known to contribute to …

Recruitment and disruption of ventral pallidal cue encoding during alcohol seeking

DJ Ottenheimer, K Wang, A Haimbaugh… - European Journal of …, 2019 - Wiley Online Library
A critical area of inquiry in the neurobiology of alcohol abuse is the mechanism by which
cues gain the ability to elicit alcohol use. Previously, we found that cue‐evoked activity in rat …

[HTML][HTML] Prefrontal cortex encodes value pop-out in visual search

M Abbaszadeh, A Panjehpour, SMA Alemohammad… - Iscience, 2023 - cell.com
Recent evidence demonstrates that long-term object value association can enhance visual
search efficiency, a phenomenon known as value pop-out. However, the neural mechanism …

Prefrontal cortex temporally multiplexes slow and fast dynamics in value learning and memory

SR Hashemirad, M Abbaszadeh, A Ghazizadeh - bioRxiv, 2024 - biorxiv.org
Previous studies have revealed segregated circuitries in basal ganglia for fast learning that
enables value adaptability and slow forgetting which underlies stable value memories …

Optimal Binning of Peri-Event Time Histograms Using Akaike Information Criterion

A Ghazizadeh, F Ambroggi - bioRxiv, 2020 - biorxiv.org
Peri-event time histograms (PETH) are widely used to study correlations between
experimental events and neuronal firing. The accuracy of firing rate estimate using a PETH …

Two distinct neuronal populations in the rat parafascicular nucleus oppositely encode the engagement in stimulus-driven reward-seeking

M Sicre, F Ambroggi, J Meffre - Current Neuropharmacology, 2024 - ingentaconnect.com
Background: The thalamus is a phylogenetically well-preserved structure. Known to densely
contact cortical regions, its role in the transmission of sensory information to the striatal …