Lycopene as a natural antioxidant used to prevent human health disorders

M Imran, F Ghorat, I Ul-Haq, H Ur-Rehman, F Aslam… - Antioxidants, 2020 - mdpi.com
Lycopene, belonging to the carotenoids, is a tetraterpene compound abundantly found in
tomato and tomato-based products. It is fundamentally recognized as a potent antioxidant …

Diet and male fertility: the impact of nutrients and antioxidants on sperm energetic metabolism

A Ferramosca, V Zara - International journal of molecular sciences, 2022 - mdpi.com
Diet might affect male reproductive potential, but the biochemical mechanisms involved in
the modulation of sperm quality remain poorly understood. While a Western diet is …

Lycopene prevents DEHP-induced Leydig cell damage with the Nrf2 antioxidant signaling pathway in mice

Y Zhao, MZ Li, Y Shen, J Lin, HR Wang… - Journal of agricultural …, 2019 - ACS Publications
As a plasticizer, di (2-ethylhexyl) phthalate (DEHP) is the most usually used phthalate.
Leydig cell is a male-specific cell, which plays a principal role in spermatogenesis and …

Lycopene Attenuates Di (2-ethylhexyl) Phthalate-Induced Mitochondrial Damage and Inflammation in Kidney via cGAS–STING Signaling

MZ Li, XY Dai, YX Zhao, XW Li, Y Zhao… - Journal of Agricultural …, 2022 - ACS Publications
Di (2-ethylhexyl) phthalate (DEHP) is a highly harmful and persistent environmental
pollutant. Due to its unique chemical composition, it frequently dissolves and enters the …

[HTML][HTML] Lycopene and male infertility

D Durairajanayagam, A Agarwal, C Ong… - Asian journal of …, 2014 - journals.lww.com
Excessive amounts of reactive oxygen species (ROS) cause a state of oxidative stress,
which result in sperm membrane lipid peroxidation, DNA damage and apoptosis, leading to …

Aryl hydrocarbon receptor as a target for lycopene preventing DEHP-induced spermatogenic disorders

Y Zhao, J Lin, M Talukder, SY Zhu, MZ Li… - Journal of agricultural …, 2020 - ACS Publications
Di (2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer to improve product
flexibility and workability. Lycopene (LYC) is a natural compound and has promising …

[HTML][HTML] Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor 2 signaling pathway

L Cao, J Zhao, L Ma, J Chen, J Xu, SU Rahman… - Ecotoxicology and …, 2021 - Elsevier
Zearalenone (ZEA) has an estrogenic effect and often causes reproductive damage. Pigs
are particularly sensitive to it. Lycopene (LYC) is a type of fat-soluble natural carotenoid that …

Acute and 28-days repeated dose sub-acute toxicity study of gallic acid in albino mice

BC Variya, AK Bakrania, P Madan, SS Patel - Regulatory Toxicology and …, 2019 - Elsevier
Gallic acid is a phenolic acid ubiquitously present in numerous medicinal plants and food
beverages. Gallic acid is also a potent anti-oxidant phytochemical possessing numerous …

The effects of lycopene supplement on the spermatogram and seminal oxidative stress in infertile men: A randomized, double‐blind, placebo‐controlled clinical trial

M Nouri, R Amani, M Nasr‐Esfahani… - Phytotherapy …, 2019 - Wiley Online Library
Infertility is a major, worldwide problem that is affected, and mediated, by several factors, in
particular, oxidative stress. Thus, the aim of this study was to evaluate the effect of lycopene …

[HTML][HTML] Lycopene ameliorates aflatoxin B1-induced testicular lesion by attenuating oxidative stress and mitochondrial damage with Nrf2 activation in mice

W Huang, Z Cao, Y Cui, S Huo, B Shao, M Song… - Ecotoxicology and …, 2023 - Elsevier
Highlights•Lycopene (LYC) has protective effect against Aflatoxin B 1 (AFB 1)-induced
testicular lesion.•LYC mitigates AFB 1-induced testicular lesion via ameliorating oxidative …