Metabolic diseases, featured with dysregulated energy homeostasis, have become major
global health challenges. Patients with metabolic diseases have high probability to manifest …

Diabetic nephropathy (DN) is a serious complication of diabetes, and its progression is
influenced by factors like oxidative stress, inflammation, cell death, and fibrosis. Compared …

Introduction The cardiometabolic risk associated with metabolically healthy obesity remains
the subject of debate. It is unclear whether changes in metabolically healthy obesity status …

Exhaustive exercise (EE) induces liver injury and has recently gained much attention.
Sulforaphane (SFN) can protect the liver from inflammation and oxidative stress. However …

Curcumin (CUR) is a lipophilic natural polyphenol that can be isolated from the rhizome of
turmeric. Studies have proposed that CUR possesses a variety of biological activities. Due to …

Obesity is an epidemic all around the world. Weight loss interventions that are effective differ
from each other with regard to various lipidomic responses. Here, we aimed to find lipidomic …

T2DM is known to cause disturbances in glucose homeostasis and negative changes in the
heart muscle, while aging and diabetes are recognized risk factors for CVD. Given this, our …

Aims Disruption of the insulin signaling pathway leads to insulin resistance (IR). IR is
characterized by impaired glucose and lipid metabolism. Elevated levels of circulating …

There is a notable correlation between mitochondrial homeostasis and metabolic disruption.
In this review, we report that obesity-induced disruption of mitochondrial homeostasis …

Recently, the gut microbiota has been recognized as a novel endocrine organ in the human
body. It produces various bioactive metabolites and participates in metabolic processes. In …