The proarrhythmic effects of hypothermia in atria isolated from 5-HT4-receptor-overexpressing mice

U Gergs, T Brückner, B Hofmann, J Neumann - European Journal of …, 2021 - Elsevier
We investigated whether hypothermia would be arrhythmogenic in mice that overexpress
the human 5-HT 4 receptor only in their cardiac myocytes (5-HT 4-TG). Contractile studies …

[HTML][HTML] Temperature alters the inotropic, chronotropic and proarrhythmic effects of histamine in atrial muscle preparations from humans and H2-receptor …

RJR Hoffmann, U Gergs, B Hofmann… - Naunyn-Schmiedeberg's …, 2023 - Springer
We investigated whether hypothermia and hyperthermia can alter the efficacy and potency
of histamine at increasing the force of cardiac contractions in mice that overexpress the …

Effect of Hypothermia on Myocardial Depolarization and Repolarization in Neonates with Hypoxic–Ischemic Encephalopathy Due to Asphyxia

M Manabe, M Fujino, H Kusuki, T Sadanaga, T Hata… - Pediatric …, 2022 - Springer
Therapeutic hypothermia (TH) is effective for neonatal hypoxic–ischemic encephalopathy
(HIE). The combination of abnormal myocardial repolarization and fatal arrhythmia in …

Catecholaminergic Polymorphic Ventricular Tachycardia: Challenges During Resuscitation and Post–Cardiac Arrest Care

V Carinci, L Gamberini, C Coniglio, G Casella… - The Journal of …, 2020 - Elsevier
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare
channelopathy involving cardiac calcium metabolism that often shows up at an early age …

[HTML][HTML] Beneficial Electrophysiological Effects of Rotigaptide Are Unable to Suppress Therapeutic Hypothermia-Provoked Ventricular Fibrillation in Failing Rabbit …

HL Lee, PC Chang, HT Wo, HT Liu, MS Wen… - Frontiers in …, 2021 - frontiersin.org
Aims: Whether therapeutic hypothermia (TH) is proarrhythmic in preexisting failing hearts
with acute ischemia–reperfusion (IR) injury is unknown. Additionally, the effectiveness of …

Therapy-resistant ventricular arrhythmias developed more often in advanced than in therapeutic mild hypothermic condition

O Saitoh, J Watanabe, A Oikawa, A Sugai… - International Heart …, 2019 - jstage.jst.go.jp
Therapy-resistant ventricular arrhythmias can occur during accidental advanced
hypothermic conditions. On the other hand, hypothermic therapy using mild cooling has …

Osborn J wave は偶発性低体温症の重症度と関連しない

横山龍人, 富田源, 堀江紗希, 齋藤聡子… - 日本臨床救急医学会 …, 2024 - jstage.jst.go.jp
目的: 深部体温が 35℃ 未満に低下した状態である偶発性低体温症 (accidental hypothermia,
以下 AH と略す) ではしばしば心電図で Osborn J wave (以下 OW と略す) を認める. 本研究は OW …