Colorectal cancer (CRC) is a leading cause of death among cancer patients. This
heterogeneous disease is characterized by alterations in multiple molecular pathways …

Mitochondria are well known for their role in ATP production and biosynthesis of
macromolecules. Importantly, increasing experimental evidence points to the roles of …

Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

Abstract Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …

Targeted cancer therapy aims to achieve specific elimination of cancerous but not normal
cells. Recently, PIWI proteins, a subfamily of the PAZ-PIWI domain (PPD) protein family …

Simple Summary The PI3K/AKT signaling pathway plays critical roles in regulating a series
of cellular changes to promote tumor development and progression. The cytoskeletal …

The actin cytoskeleton is of fundamental importance for numerous cellular processes,
including intracellular transport, cell plasticity, and cell migration. However, functions of …

The clinical utility of circulating tumor cells (CTC) as a non-invasive multipurpose biomarker
is broadly recognized. The earliest methods for enriching CTCs from whole blood rely on …

Cell aggregation is frequently impaired during the growth of primary tumors and the
formation of metastatic lesions. Cell aggregation depends on cell–cell adhesion; however …

A deeper understanding of colorectal cancer (CRC) biology would help to identify specific
early diagnostic markers. Here, we conducted quantitative proteomics on FFPE healthy …