Spontaneous and therapeutic-induced mechanisms of functional recovery after stroke

JM Cassidy, SC Cramer - Translational stroke research, 2017 - Springer
With increasing rates of survival throughout the past several years, stroke remains one of the
leading causes of adult disability. Following the onset of stroke, spontaneous mechanisms of …

Brain networks and their relevance for stroke rehabilitation

AG Guggisberg, PJ Koch, FC Hummel… - Clinical …, 2019 - Elsevier
Stroke has long been regarded as focal disease with circumscribed damage leading to
neurological deficits. However, advances in methods for assessing the human brain and in …

Behavioural clusters and predictors of performance during recovery from stroke

LE Ramsey, JS Siegel, CE Lang, M Strube… - Nature human …, 2017 - nature.com
We examined the patterns and variability of post-stroke recovery in multiple behavioural
domains. A large cohort of first-time stroke patients with heterogeneous lesions was studied …

Stroke and the connectome: how connectivity guides therapeutic intervention

G Silasi, TH Murphy - Neuron, 2014 - cell.com
Connections between neurons are affected within 3 min of stroke onset by massive ischemic
depolarization and then delayed cell death. Some connections can recover with prompt …

Neural function, injury, and stroke subtype predict treatment gains after stroke

E Burke Quinlan, L Dodakian, J See… - Annals of …, 2015 - Wiley Online Library
Objective This study was undertaken to better understand the high variability in response
seen when treating human subjects with restorative therapies poststroke. Preclinical studies …

Implementation of wearable sensing technology for movement: pushing forward into the routine physical rehabilitation care field

CE Lang, J Barth, CL Holleran, JD Konrad, MD Bland - Sensors, 2020 - mdpi.com
While the promise of wearable sensor technology to transform physical rehabilitation has
been around for a number of years, the reality is that wearable sensor technology for the …

Exploring the role of accelerometers in the measurement of real world upper-limb use after stroke

KS Hayward, JJ Eng, LA Boyd, B Lakhani… - Brain …, 2016 - cambridge.org
The ultimate goal of upper-limb rehabilitation after stroke is to promote real-world use, that
is, use of the paretic upper-limb in everyday activities outside the clinic or laboratory …

Enhanced interhemispheric functional connectivity compensates for anatomical connection damages in subcortical stroke

J Liu, W Qin, J Zhang, X Zhang, C Yu - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Motor recovery after stroke has been shown to be correlated
with both the fractional anisotropy (FA) of the affected corticospinal tract (CST) and the …

[HTML][HTML] In vivo widefield calcium imaging of the mouse cortex for analysis of network connectivity in health and brain disease

JV Cramer, B Gesierich, S Roth, M Dichgans, M Düring… - Neuroimage, 2019 - Elsevier
The organization of brain areas in functionally connected networks, their dynamic changes,
and perturbations in disease states are subject of extensive investigations. Research on …

Structural connectome disruption at baseline predicts 6‐months post‐stroke outcome

A Kuceyeski, BB Navi, H Kamel, A Raj… - Human brain …, 2016 - Wiley Online Library
In this study, models based on quantitative imaging biomarkers of post‐stroke structural
connectome disruption were used to predict six‐month outcomes in various domains …