Research progress on the role of lncRNA–miRNA networks in regulating adipogenic and osteogenic differentiation of bone marrow mesenchymal stem cells in …

F An, X Wang, C Wang, Y Liu, B Sun, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Osteoporosis (OP) is characterized by a decrease in osteoblasts and an increase in
adipocytes in the bone marrow compartment, alongside abnormal bone/fat differentiation …

MIR4435-2HG is a potential pan-cancer biomarker for diagnosis and prognosis

C Zhong, Z Xie, L Zeng, C Yuan, S Duan - Frontiers in Immunology, 2022 - frontiersin.org
The lncRNA MIR4435-2 host gene (MIR4435-2HG) is located on human chromosome 2q13,
and its expression is up-regulated in 18 tumors. MIR4435-2HG participates in 6 signaling …

ANXA2P2/miR-9/LDHA axis regulates Warburg effect and affects glioblastoma proliferation and apoptosis

P Du, Y Liao, H Zhao, J Zhang, K Mu - Cellular Signalling, 2020 - Elsevier
Background Aerobic glycolysis is a unique tumor cell phenotype considered as one of the
hallmarks of cancer. Aerobic glycolysis can accelerate tumor development by increasing …

Coding of glioblastoma progression and therapy resistance through long noncoding RNAs

A Zottel, N Šamec, A Videtič Paska, I Jovčevska - Cancers, 2020 - mdpi.com
Glioblastoma is the most aggressive and lethal primary brain malignancy, with an average
patient survival from diagnosis of 14 months. Glioblastoma also usually progresses as a …

LncRNA MIR4435-2HG triggers ovarian cancer progression by regulating miR-128-3p/CKD14 axis

L Zhu, A Wang, M Gao, X Duan, Z Li - Cancer cell international, 2020 - Springer
Background Accumulating studies showed that long noncoding RNAs (lncRNAs) played
vital roles in cancer progression. LncRNA MIR4435-2HG was proved to act as an oncogene …

MicroRNA-19b-3p promotes cell proliferation and osteogenic differentiation of BMSCs by interacting with lncRNA H19

G Xiaoling, L Shuaibin, L Kailu - BMC medical genetics, 2020 - Springer
Background To investigated the role of miR-19b-3p in regulating bone marrow
mesenchymal stem cell (BMSC) proliferation and osteoblast differentiation. Methods The …

Critical role of HOX transcript antisense intergenic RNA (HOTAIR) in gliomas

E Angelopoulou, YN Paudel, C Piperi - Journal of Molecular Medicine, 2020 - Springer
Despite extensive research, gliomas are associated with high morbidity and mortality, mainly
attributed to the rapid growth rate, excessive invasiveness, and molecular heterogeneity, as …

Inhibition of MIR4435-2HG on invasion, migration, and EMT of gastric carcinoma cells by mediating MiR-138-5p/Sox4 axis

LF Gao, W Li, YG Liu, C Zhang, WN Gao… - Frontiers in …, 2021 - frontiersin.org
Background The previous investigations have identified that long non-coding RNA
(lncRNAs) act as crucial regulators in gastric carcinoma. However, the function of lncRNA …

[HTML][HTML] MIR4435-2HG: A newly proposed lncRNA in human cancer

M Zhang, X Yu, Q Zhang, Z Sun, Y He, W Guo - Biomedicine & …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) play important roles in the occurrence and progression of
tumors. Extensive research has contributed to the current understanding of the critical roles …

Negative pressure promotes macrophage M1 polarization after Mycobacterium tuberculosis infection via the lncRNA XIST/microRNA–125b–5p/A20/NF–κB axis

XB Luo, LT Li, JC Xi, HT Liu, Z Liu… - Annals of the New …, 2022 - Wiley Online Library
Experiments have demonstrated the regulation of long noncoding RNA (lncRNA) in
tuberculosis (TB), and negative pressure treatment has been associated with the alleviation …